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Alignment based on pLDDT

Posted: Mon Mar 18, 2024 4:56 pm
by antonia.feilden
To whom it may concern,

I have read: viewtopic.php?f=3&t=652&p=1220&hilit=pl ... fe7c#p1220

Does US-Align take into account pLDDT and BAT scores for AlphaFold and PDB crystal structures? Both are residue location confidence metrics. I believe this could enhance the tool and be implemented using the summation of relative weights of the aligned residues.

Best wishes,
Antonia

Re: Alignment based on pLDDT

Posted: Thu May 02, 2024 7:11 pm
by zcx@umich.edu
No, US-align cannot consider pLDDT score.