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Homologous dimer modeling

Posted: Wed Apr 17, 2024 12:36 pm
by 238527177@fzu.edu.cn
Hello, Zhang Yang's research team
Firstly, thank you for providing a free modeling platform. I want to create a homologous dimer composed of two protein monomers, but I'm not sure if i-tasser can input the sequences of two protein monomers at the same time, or can only model one sequence at a time, and then use other software to merge the structures later?
Looking forward to your reply.

Re: Homologous dimer modeling

Posted: Wed Apr 17, 2024 4:26 pm
by jlspzw
Dear user,

You can try https://zhanggroup.org/DMFold/, put two copies of your monomer sequences, and then it is dimmer.

Best Regards
Wei Zheng

Re: Homologous dimer modeling

Posted: Thu Apr 18, 2024 12:52 am
by 238527177@fzu.edu.cn
Thank you for your reply´╝ü