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I have some questions about ResPRE

Posted: Thu Jun 17, 2021 6:51 am
by cuilei
Hi, hello!
I sincerely want to ask, in the ResPRE training process, how to deal with the problem of extremely imbalanced positive and negative samples?

In all training sets, only a few residue pairs are in contact. Most of the residues are not touched. In this case, the training model will easily overfit. How to deal with this situation? :D :D :D

Re: I have some questions about ResPRE

Posted: Thu Jun 17, 2021 2:30 pm
by liyangum
We did see the existence of imbalanced positive and negative samples. But we do not think that it is a problem.
Of course, you can set larger weights or other regular settings to try to make it more balance during the training.