How can I input multi-chain sequence as fasta?

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jayjayel
Posts: 1
Joined: Tue Dec 27, 2022 12:58 pm

How can I input multi-chain sequence as fasta?

Post by jayjayel »

Hi,

I've tried to input multi-chain sequence as below.

========================================
>A
EVQLVESGGGLVQPGGSLRLSCAASGFNIHSSSIHWVRQAPGKGLEWVAATYSSFGSITYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARYHHPFGYALDYWGQGTLVTVSSGGGGSGGGGSGGGGSDIQMTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQGVYLFTFGQGTKVEIKRTV
>B
SKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGRDAEVLCMDY
=========================================

However, it didn't work.

How can I predict multi-chain model by D-I-TASSER?

Thank you.

JL
jlspzw
Posts: 233
Joined: Tue May 04, 2021 5:04 pm

Re: How can I input multi-chain sequence as fasta?

Post by jlspzw »

Dear user,

D-I-TASSER currently does not support multi-chain modeling. We are working on a new server and will let it be released soon.

You can try this link temporarily, but the waiting time may be slightly longer since we are not complete it yet.

https://zhanggroup.org/DeepMSAFold/

Best
IT Team
donglg13
Posts: 2
Joined: Fri Jan 13, 2023 6:57 am

Re: How can I input multi-chain sequence as fasta?

Post by donglg13 »

Hi Zhanglab,

Thank you for the server. May I ask whether the stand-alone DeepMSAFold-multimer be available in the nearby feature?

Best,
Liguo
jlspzw
Posts: 233
Joined: Tue May 04, 2021 5:04 pm

Re: How can I input multi-chain sequence as fasta?

Post by jlspzw »

Dear user,

We are working on it, and the package will be available after our manuscript has been published.

Best
IT Team
donglg13
Posts: 2
Joined: Fri Jan 13, 2023 6:57 am

Re: How can I input multi-chain sequence as fasta?

Post by donglg13 »

Hi,

Is the DeepMSAfold-multimer server available now?

Liguo
jlspzw
Posts: 233
Joined: Tue May 04, 2021 5:04 pm

Re: How can I input multi-chain sequence as fasta?

Post by jlspzw »

This server will be available after the paper is published.
If you have targets (should not be too much), you can paste them here, and we can manually do them for you.
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