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I-TASSER-MTD Download

I-TASSER-MTD Suite is a package of standalone programs for predicting the structure and function of multi-domain proteins. The user manuals are at README.txt. Please report bugs and questions at Zhang Lab Service System Discussion Board. The I-TASSER-MTD Suite is free for academic and non-profit researchers.

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I-TASSER-MTD library download:

• multidomain_protein_CA.tar.gz (~184MB): Multi-domain protein structure library (for I-TASSER-MTD, analogous template, optional).
• uniclust30_2017_04_hhsuite.tar.gz (~24.9GB): Uniclust30 library (for I-TASSER-MTD, DeepMSA).
• uniref90.fasta.gz (~29.7GB): UniRef90 library (for I-TASSER-MTD, DeepMSA).
• metaclust_2017_05.fasta.gz (~60.4GB): Metaclust library (for I-TASSER-MTD, DeepMSA).
• CE (~7.5GB): CEthreader library (for I-TASSER-MTD, LOMETS2 and CEthreader).
• PDB (~1.5GB): non-redundant protein structures from PDB (for I-TASSER-MTD, LOMETS2, MUSTER, CEthreader and SEGMER).
• MTX (~526MB): Sequence profiles from PSI-BLAST search (for I-TASSER-MTD, LOMETS2, MUSTER and SEGMER).
• DEP (~315MB): Depth-dependent structure profiles of templates (for I-TASSER-MTD, LOMETS2, MUSTER and SEGMER).
• SIG (~334MB): Residue environmental profiles of templates (for I-TASSER-MTD, LOMETS2).
• CNT (~133MB): Side-chain center contacts of templates (for I-TASSER-MTD, LOMETS2).
• dotProfile (~173MB): Sequence profiles from PSI-BLAST search (for I-TASSER-MTD, LOMETS2).
• stride (~3MB): Seven state secondary structure assignment (for I-TASSER-MTD, LOMETS2).
• summary1 (~66MB): Sequence, secondary structure, solvent accessibilty, phi/psi angles (for I-TASSER-MTD, LOMETS2, MUSTER and SEGMER).
• summary2 (~185MB): Training data for phi/psi prediction and contact prediction by SVM (for I-TASSER-MTD, LOMETS2, MUSTER and SEGMER).
• Bfactor (~155MB): B-factor values of templates (for B-factor profile prediction).

      Instructions on how to configure the libraries are available at README.txt.

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I-TASSER-MTD download:

• For academic users, please click I-TASSER-MTD to download the I-TASSER-MTD Suite.
• If you need I-TASSER-MTD Suite for a commercial use, please contact us through yangzhanglabumich.edu.