Search found 7 matches

by cuilei
Thu Jun 17, 2021 6:51 am
Forum: Main Forum
Topic: I have some questions about ResPRE
Replies: 1
Views: 131

I have some questions about ResPRE

Hi, hello! I sincerely want to ask, in the ResPRE training process, how to deal with the problem of extremely imbalanced positive and negative samples? In all training sets, only a few residue pairs are in contact. Most of the residues are not touched. In this case, the training model will easily ov...
by cuilei
Thu Jun 03, 2021 4:21 am
Forum: Main Forum
Topic: I have some questions about ResPRE
Replies: 5
Views: 439

Re: I have some questions about ResPRE

Thank you very much! I figured out the problem.:D :D :D
by cuilei
Sat May 29, 2021 1:42 pm
Forum: Main Forum
Topic: I encountered some problems in the process of ResPRE building the contact matrix.
Replies: 1
Views: 203

I encountered some problems in the process of ResPRE building the contact matrix.

Dear Zhang Yang Lab: Hello, I encountered some problems in the process of ResPRE building the contact matrix. :D :D 1. Download the protein structure file in the PDB. The PDBID of this protein is 1F88. Its sequence length is 348, as shown in Figure 1. But only 338 residues have structural informatio...
by cuilei
Wed May 26, 2021 5:37 am
Forum: Main Forum
Topic: I have some questions about ResPRE
Replies: 5
Views: 439

Re: I have some questions about ResPRE

Sincerely thank you for your detailed answer. Thank you very much! :D :D :D In addition, I have another question. Q:Does the process of training ResPRE use supervised learning or unsupervised learning? If it is supervised learning, the sequence needs to be labeled before training. So what is this la...
by cuilei
Tue May 25, 2021 1:30 am
Forum: Main Forum
Topic: I have some questions about ResPRE
Replies: 5
Views: 439

I have some questions about ResPRE

Dear zhangyang laboratory: Hello! I am a student who is new to bioinformatics, and I am studying the thesis of ResPRE recently. ResPRE uses the coupling precision matrix to achieve high-accuracy protein contact prediction. It has achieved excellent results. Is an outstanding work.I sincerely hope th...
by cuilei
Mon May 24, 2021 6:58 am
Forum: Main Forum
Topic: I have some questions about the formula in the ResPRE paper
Replies: 2
Views: 344

Re: I have some questions about the formula in the ResPRE paper

I clearly figured out this problem. Thank you for your answers sincerely. :D :D :D
by cuilei
Sun May 23, 2021 6:36 am
Forum: Main Forum
Topic: I have some questions about the formula in the ResPRE paper
Replies: 2
Views: 344

I have some questions about the formula in the ResPRE paper

I would like to ask about the formula 1 in section 2.2.1.
How are the formulas for fi (a) andr fi j(a,b) derived? Or is this formula derived in another paper? Can provide some relevant papers?
Thanks!