Zhanglab forum

Dear Felecia, You’re absolutely right that the current standalone I-TASSER package does not include a generator for the index.html file. However, the output package from our online server does provide an index.html file to facilitate local viewing of the results after download. We plan to i ...

You can do it using I-TASSER-MTD (https://zhanggroup.org/I-TASSER-MTD/), which was designed for modeling large-size proteins up to 3000 AA with multiple domains.

The TM-score shown on the I-TASSER results page is not an actual TM-score, but an estimated value based on simulation parameters. We only provide this estimated TM-score for model 1, as the estimates for other models are less reliable. If you still wish to obtain an estimated TM-score for other ...

There seems to be an issue in the final step of structure refinement, which we are currently investigating and working to resolve. In the meantime, you may use FG-MD (https://zhanglab.comp.nus.edu.sg/FG-MD/) or ModRefiner (https://zhanglab.comp.nus.edu.sg/ModRefiner/) to correct local structural ...

Dear anhuifei, Thank you for using DMFold, and we’re glad to hear that you’ve received the predicted structure for your job DMF042779492. To view the interaction sites between the two proteins, we suggest the following steps: 1. Visualize the Complex in PyMOL The predicted complex structure file (us ...

Dear User, please note that our servers have been permanently moved to https://zhanggroup.org/. Kindly use this new URL to access services and submit your jobs. Thank you for your attention.

Dear TX, We sincerely apologize for the delay in processing your COACH job. Our servers were recently migrated to a new high-performance computing (HPC) cluster, which is now permanently hosted at https://zhanggroup.org/services/. The transition has been completed, and all services, including COACH ...

Yes, many software, such as our software, and Modeller, can do homology modeling while keeping certain residues.

Yes, We have not yet finished it!

Hello Zhang, I once again turn to you for some clarification. I have been playing around with the dataset and I ran into a situation. The main file "BioLiP.txt.gz" has about 800.000+ entries (redundant set), all kinds of ligands included. When downloading the weekly updates (redundant set), I am ...