Calculation of TM-score and rmsd for all predicted models by I-TASSER

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FYaghoobizadeh
Posts: 1
Joined: Tue Jul 23, 2024 3:41 pm

Calculation of TM-score and rmsd for all predicted models by I-TASSER

Post by FYaghoobizadeh »

I submitted my job on the I-TASSER server (ID ) and get the results. According to the server help page, a higher c-score (i.e., more positive) is better. Is it true? accordingly between 5 top predicted models for my structure (with C-score -2.72, -2.32, -1.20, -3.39, and -2.94) I choose the model 3 with c-score -1.20. However, TM-score and RMSD are only provided for model 1 (C-score -2.72). In this regard, I validate the structures of model1 and model3 by saves v6.0 and proSA servers and get the better results for model 3.
How could we obtain these indexes for other models? Moreover, I compared the 3d of model3 with 10-top ranked model presented in I-TASSER results page with Swiss model structural assessment tool. Is this work to calculate TM-score and RMSD OK?
I will be very thankful if you guide me as rapid as possible.
Sincerely yours