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BioLiP

Structure of PDB 3gp8 Chain A Binding Site BS01

Receptor Information
>3gp8 Chain A (length=551) Species: 243230 (Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QGLERRLLAGLQGLGLTINQAQRAVKHFGADALDRLEKDLFTLTEVEGIG
FLTADKLWQARGGALDDPRRLTAAAVYALQLAGTQAGHSFLPRSRAEKGV
VHYTRVTPGQARLAVETAVELGRLSEDDSPLFAEAAATGEGRIYLPHVLR
AEKKLASLIRTLLATPPADDDWAVPKKARKGLSEEQASVLDQLAGHRLVV
LTGGPGTGKSTTTKAVADLAESLGLEVGLCAPTGKAARRLGEVTGRTAST
VHRLLGYGPQGFRHNHLEPAPYDLLIVDEVSMMGDALMLSLLAAVPPGAR
VLLVGDTDQLPPVDAGLPLLALAQAAPTIKLTQVYRQAAKNPIIQAAHGL
LHGEAPAWGDKRLNLTEIEPDGGARRVALMVRELGGPGAVQVLTPMRKGP
LGMDHLNYHLQALFNPGEGGVRIAEGEARPGDTVVQTKNIFNGTLGMVLK
AEGARLTVDNVVELTGAELFNLQLGYALTVHRAQGSEWGTVLGVLHEAHM
PMLSRNLVYTALTRARDRFFSAGSASAWQIAAARQREARNTALLERIRAH
L
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3gp8 Mechanistic basis of 5'-3' translocation in SF1B helicases.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Q237 P389 T390 G391 T407 H409 R410 Y414 P416 M439 V470 D471 M553 R554 K555 N596 N604 T644 H646 R647 P666 M667
Binding residue
(residue number reindexed from 1)		Q85 P232 T233 G234 T250 H252 R253 Y257 P259 M282 V313 D314 M396 R397 K398 N439 N442 T479 H481 R482 P501 M502
Enzymatic activity
Enzyme Commision number 5.6.2.3: DNA 5'-3' helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0016887 ATP hydrolysis activity
GO:0043139 5'-3' DNA helicase activity
Biological Process
GO:0032508 DNA duplex unwinding

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Molecular Function
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Biological Process
External links
PDB RCSB:3gp8, PDBe:3gp8, PDBj:3gp8
PDBsum3gp8
PubMed19490894
UniProtQ9RT63|RECD2_DEIRA ATP-dependent RecD2 DNA helicase (Gene Name=recD2)

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