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BioLiP

Structure of PDB 4ol8 Chain A Binding Site BS01

Receptor Information
>4ol8 Chain A (length=390) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVWLQQKYREIIRNDLPPPVKHDIEIKPGARLPRLQPYHVTEKNEQEINK
IVQKLLDNKFIVPSKSPCSSPVVLVPKTFRLCVDYRTLNKATISDPFPLP
RIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYTV
MPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDTV
LERLKNENLIVKKKKCKFEETEFLGYSIGIQKIAPLQHKCAAIRDFPTPK
TVKQAQRFLGMINYYRRFIPNCSKIAQPITEKQDKAIDKLKDAPFNNKAN
YRLTTDASKDGIGAVLEEVDNKNKLVGVVGYFSKSLEYPAGELELLGIIK
ALHHFRYMLHGKHFTLRTNHARRVQRWLDDLATYDFTLEY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ol8 Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		C114 V115 R118 F185 G186 V188 P191 N297
Binding residue
(residue number reindexed from 1)		C82 V83 R86 F153 G154 V156 P159 N263
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.26.4: ribonuclease H.
3.4.23.-
External links
PDB RCSB:4ol8, PDBe:4ol8, PDBj:4ol8
PDBsum4ol8
PubMed24608367
UniProtQ99315|YG31B_YEAST Transposon Ty3-G Gag-Pol polyprotein (Gene Name=TY3B-G)

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