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Structure of PDB 7qbc Chain A Binding Site BS01

Receptor Information >7qbc Chain A (length=298) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] APSLSNLFYDPTYNPGQSTINYTSIYGNGSTITFDELQGLVNSTVTQAIM FGVRCGAAALTLIVMWMTSRSRKTPIFIINQVSLFLIILHSALYFKYLLS NYSSVTYALTGFPQFISRGDVHVYGATNIIQVLLVASIETSLVFQIKVIF TGDNFKRIGLMLTSISFTLGIATVTMYFVSAVKGMIVTYNDVSATQDKYF NASTILLASSINFMSFVLVVKLILAIRSRRFLGLKQFDSFHILLIMSCQS LLVPSIIFILAYSLKPNQGTDVLTTVATLLAVLSLPLSSMWATAANNA

Ligand information >7qbc Chain I (length=13) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] WHWLQLKPGQPMY

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 7qbc Activation mechanism of the class D fungal GPCR dimer Ste2. Resolution 3.53 Å Binding residue (original residue number in PDB) Q51 H94 Y98 Y101 Y128 T131 N132 Q135 Y181 S184 D201 K202 F204 N205 I263 Y266 S267 K269 N271 D275 T278 Binding residue (residue number reindexed from 1) Q47 H90 Y94 Y97 Y124 T127 N128 Q131 Y177 S180 D197 K198 F200 N201 I259 Y262 S263 K265 N267 D271 T274

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0004930 G protein-coupled receptor activity GO:0004932 mating-type factor pheromone receptor activity GO:0004934 mating-type alpha-factor pheromone receptor activity GO:0005515 protein binding

	Biological Process
GO:0000750	pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0000755	cytogamy
GO:0007186	G protein-coupled receptor signaling pathway
GO:0019236	response to pheromone

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0038038	G protein-coupled receptor homodimeric complex

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