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Structure of PDB 7tfl Chain A Binding Site BS01

Receptor Information >7tfl Chain A (length=338) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] REEDKLWTVKYAPTNLQQVCGNKGSVMKLKNWLANWENSKDGSGVFRAAM LYGPPGIGKTTAAHLVAQELGYDILEKHFVIIMDEVDGMSGGDRGGVGQL AQFCRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANSIKSRLMTI AIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINEIS KAWEKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTPL MIQENYLSTRPSVLKPGQSHLEAVAEAANCISLGDIVEKKIRSSEQLWSL LPLHAVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAK

Ligand information >7tfl Chain I (length=13) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] tttatgtactcgt

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 7tfl Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair. Resolution 3.33 Å Binding residue (original residue number in PDB) D586 R632 Q636 W638 W669 L670 Binding residue (residue number reindexed from 1) D246 R292 Q296 W298 W329 L330

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003689 DNA clamp loader activity GO:0005515 protein binding GO:0005524 ATP binding GO:0016887 ATP hydrolysis activity

	Biological Process
GO:0000278	mitotic cell cycle
GO:0006260	DNA replication
GO:0006261	DNA-templated DNA replication
GO:0006271	DNA strand elongation involved in DNA replication
GO:0006272	leading strand elongation
GO:0006281	DNA repair
GO:0006298	mismatch repair
GO:0051301	cell division

	Cellular Component
GO:0005634	nucleus
GO:0005663	DNA replication factor C complex

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