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BioLiP

Structure of PDB 8trq Chain A Binding Site BS01

Receptor Information
>8trq Chain A (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFDT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8trq T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4
Resolution2.75 Å
Binding residue
(original residue number in PDB)		Q9 A52 S53 F54 N62 V65 D66 N69 I72 M73
Binding residue
(residue number reindexed from 1)		Q7 A50 S51 F52 N60 V63 D64 N67 I70 M71
External links
PDB RCSB:8trq, PDBe:8trq, PDBj:8trq
PDBsum8trq
PubMed39043656
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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