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Structure of PDB 4v7u Chain AT Binding Site BS01

Receptor Information >4v7u Chain AT (length=85) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] NIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFN EMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA

Ligand information >4v7u Chain AA (length=1533) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] aauugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa cacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacga guggcggacgggugaguaaugucugggaaacugccugauggagggggaua acuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagagg gggaccuucgggccucuugccaucggaugugcccagaugggauuagcuag uaggugggguaacggcucaccuaggcgacgaucccuagcuggucugagag gaugaccagccacacuggaacugagacacgguccagacuccuacgggagg cagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugcc gcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagga agggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaagc accggcuaacuccgugccagcagccgcgguaauacggagggugcaagcgu uaaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaagucag augugaaauccccgggcucaaccugggaacugcaucugauacuggcaagc uugagucucguagagggggguagaauuccagguguagcggugaaaugcgu agagaucuggaggaauaccgguggcgaaggcggcccccuggacgaagacu gacgcucaggugcgaaagcguggggagcaaacaggauuagauacccuggu aguccacgccguaaacgaugucgacuuggagguugugcccuugaggcgug gcuuccggagcuaacgcguuaagucgaccgccuggggaguacggccgcaa gguuaaaacucaaaugaauugacgggggcccgcacaagcgguggagcaug ugguuuaauucgaugcaacgcgaagaaccuuaccuggucuugacauccac ggaaguuuucagagaugagaaugugccuucgggaaccgugagacaggugc ugcauggcugucgucagcucguguugugaaauguuggguuaagucccgca acgagcgcaacccuuauccuuuguugccagcgguccggccgggaacucaa aggagacugccagugauaaacuggaggaagguggggaugacgucaaguca ucauggcccuuacgaccagggcuacacacgugcuacaauggcgcauacaa agagaagcgaccucgcgagagcaagcggaccucauaaagugcgucguagu ccggauuggagucugcaacucgacuccaugaagucggaaucgcuaguaau cguggaucagaaugccacggugaauacguucccgggccuuguacacaccg cccgucacaccaugggaguggguugcaaaagaaguagguagcuuaaccuu cgggagggcgcuuaccacuuugugauucaugacuggggugaagucguaac aagguaaccguaggggaaccugcgguuggauca .......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..... <<<.<<<..<<<..<<.<...<<<<<.<<........>>.>>.>>>.>.. >>>>>......<<.......<<<<<<<..<<...<<<<<<<.<.<<.... .<<<<<......>>>>>......>>.>.....<<<....>>>....<<<< <<..<<....>>>>>>>>.>>>>>>>..>>.>>>>>>><<<....<<<.. <<<<<<<.........>>>>>>>>>>......>>>..<<<<<<<<....> >>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>. ..>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>>>> >>..<<<<.......<<<....>>>......>>>>...<.<<<<<..... .<.<<<<<<.<.......>>>.>>>>.>........>>>>>....>..<< <<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>> >>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<< <<<<......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>> ...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>>.. ....>>>>>>>>...........<<....>>.>>>>>>>..>>>>.>>>> ...>>>...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>.. .>>>>>>>>..........<<<<<<.<<<<<<<<<<<<<.....>>>>>> >>>>>>>..<<..))>>.....>>>>>>.>>>.<<<......<<<<.... >>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<< <<<<......<<........>>..........<<<<<<<......<<<<< <<..<<<<<<<....>>>>>>>...<<....>>..>>>>>.>>.<<<.<< <..<<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>.. >>>>>>.....<<<<.<<<<<<<...<<..<<<.....>>>>>....>>> >>>>.....<<<<<.....>>>>>........>>>>.........>>>.. .>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.... .<<<..<<...<<<....>>>...>>....>>>.....>>>>>>>..... .<....<<<<<<<........>>>>>>>....>.....>>>>>>....<< <<<<<.........>>>>>>>......>>...>>>>>>>>>>.>>....< ..<<.<.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.<<<<..<<.. ..>>.>>>>>>>>>>...>>>>>>>>>>>>..>>>.>>>>..>.>>...> .....<<<<<<<<<....>>>>>>>>>......

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 4v7u Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Resolution 3.1 Å Binding residue (original residue number in PDB) N2 K4 K8 R9 S13 A16 R17 S22 R24 S25 M26 R28 T29 K32 Q54 P55 D58 R59 K63 K68 N69 K70 R73 K75 A76 N77 Q81 Binding residue (residue number reindexed from 1) N1 K3 K7 R8 S12 A15 R16 S21 R23 S24 M25 R27 T28 K31 Q53 P54 D57 R58 K62 K67 N68 K69 R72 K74 A75 N76 Q80

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003723 RNA binding GO:0003735 structural constituent of ribosome GO:0008073 ornithine decarboxylase inhibitor activity GO:0019843 rRNA binding GO:0070181 small ribosomal subunit rRNA binding

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component