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BioLiP

Structure of PDB 4pvz Chain B Binding Site BS01

Receptor Information
>4pvz Chain B (length=422) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVE
FMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSV
EVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATW
TLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDG
PQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVV
INAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPP
LVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLL
EIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIF
NCQQNENDKIYEKAYKIIETYF
Ligand information
>4pvz Chain D (length=19) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TNKRKREQISSPKKKRKKR
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4pvz Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Q113 L115 S116 R117 E118 P121 W153 N157 A159 S160 G161 T162 Q192 W195 N199 G202 D203 W237 R244 K246 D286 G287 R321 N325 V327 T328 G329 E360 W363 N367 A370 E402 W405 N409
Binding residue
(residue number reindexed from 1)		Q26 L28 S29 R30 E31 P34 W66 N70 A72 S73 G74 T75 Q105 W108 N112 G115 D116 W150 R157 K159 D199 G200 R234 N238 V240 T241 G242 E273 W276 N280 A283 E315 W318 N322
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4pvz, PDBe:4pvz, PDBj:4pvz
PDBsum4pvz
PubMed26051712
UniProtQ02821|IMA1_YEAST Importin subunit alpha (Gene Name=SRP1)

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