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Structure of PDB 8evq Chain BJ Binding Site BS01

Receptor Information >8evq Chain BJ (length=185) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] PRAPRTYSKTYSTPKRPYESSRLDAELKLAGEFGLKNKKEIYRISFQLSK IRRAARDLLTRDEKDPKRLFEGNALIRRLVRVGVLSEDKKKLDYVLALKV EDFLERRLQTQVYKLGLAKSVHHARVLITQRHIAVGKQIVNIPSFMVRLD SEKHIDFAPTSPFGGARPGRVARRNAARKAEASGE

Ligand information >8evq Chain B5 (length=1782) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu caacggguaacggggaauaaggguucgauuccggagagggagccugagaa acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu aauucagggagguagugacaauaaauaacgauacagggcccauucggguc uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau auuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguu ggccggucggauuuccaacggggccuuuccuucuggcuaaccuugagucc uuguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguu caaagcaggcguauugcucgaauauauuagcauggaauaauagaauagga cguuugguucuauuuuguugguuucuaggaccaucguaaugauuaauagg gacggucgggggcaucaguauucaauugucagaggugaaauucuuggauu uauugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaa ucaagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucu uaaccauaaacuaugccgacuagggaucgggugguguuuuuuuaaugacc cacucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguau ggucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggag uggagccugcggcuuaauuugacucaacacggggaaacucaccaggucca gacacaauaaggauugacagauugagagcucuuucuugauuuugugggug guggugcauggccguucuuaguugguggagugauuugucugcuuaauugc gauaacgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcug guuauccacuucuuagagggacuaucgguuucaagccgauggaaguuuga ggcaauaacaggucugugaugcccuuagacguucugggccgcacgcgcgc uacacugacggagccagcgagucuaaccuuggccgagaggucuugguaau cuugugaaacuccgucgugcuggggauagagcauuguaauuauugcucuu caacgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacgu cccugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuua gugaggccucaggaucugcuuagagaagggggcaacuccaucucagagcg gagaauuuggacaaacuuggucauuuagaggaacuaaaagucguaacaag guuuccguaggugaaccugcggaaggaucauu ...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<...<......<<< .<<<..<<....<<....<<..........>>...>>.>>......<<.. <.....<<<..<<..<<....<<<..................<.....<< .<<.......>>.>>......>.........<<<<<............>> >>><...<<<<<<......(((.{((.<.<....>.>.....<......> .>>>>>>.....>...<<<<..<<<.....>>>.>>>>....>>>...>> >>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>.. ....>>>...<<<.<<<<....>>>>....>>>>>>.<<.<<<....... ...>>>.>>.<.<<....>>.>...>>>>>>.........<<<....<<< .....>>>..>>>..>....>.>.....<<<..<................ ..>...>>>......<<..<...........>..>>.........<<<<< ((......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>> >>>>.........<<<[[.....<.<<...<<<.<<....<<<<<<.<<< <..............>>>>.>>>>>>......<<<<.............. .................>>>>.....<<<<<.<<.......<<...<... ....>..<<<.....>>>....>>......>>.>>..>>>.........< <...<<<<<<<<.....)).}))).>>>>>>>>..>>.....>>....<< <<<<.<<...<<<<..<<..<<<<<<.<...<<<......>>>......> .>>>>>>..>>.......<<....>>...>>>>...>>>>>.>>>...>> >...>>.>....<<<<<<<...<...<<<<.<.....>.>>>>...>>>> >>>>..........<<<.<<.<<<..<<<<<<<<.<<<........>>>> >>>>>>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<...... <<<<....>>>>....>>>..)))).}<<<<<.<<<<<<<..<<.<<<<< <..<<<.<<<<<<......<<........>>..........<<<<<.<.. ..<<<<<........<<.<<<........>>>.>>......>>>>>...< <.<<<..<<.<<<<<<....<<<.<<<<<....>>>...<<<......>> >...>>.>>>....<<<<<.<<..<<<<..<<<<<.<.<<<<<..>>>>> .>...>>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>> >>....>>>.>>>.....>>>>>>>.....>.>>>>>...>>.>>>>.>> >.....<<<<<<<......<<.....<<..<<<<....>>>>..>>.... >>.......>>>>>>>......<....<<<<<<..........>>>>>>. ...>.....>>>>>>....<<<<<<<<.......>>>>>>>>......>> ...>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.< <<..<.<<..<...<<<<<...<<<<.<<<<....>>>>.>>>>...>>> >>...>..>>.>..>>>.>>>>>>>>...>>.>>>>...>.>>...>... ..<<<<<<<<<<..>>>>>>>>>>........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8evq Regulation of translation by ribosomal RNA pseudouridylation. Resolution 2.72 Å Binding residue (original residue number in PDB) P2 R3 P5 R6 T7 Y8 S9 K10 T11 Y12 T14 K16 R17 P18 Y19 K37 N38 K39 K40 Y43 R44 K51 E72 A75 R78 R79 R82 K120 S121 H124 Q131 R132 H133 Q139 I143 F146 R149 P163 R168 P169 G170 R171 V172 A173 N176 Binding residue (residue number reindexed from 1) P1 R2 P4 R5 T6 Y7 S8 K9 T10 Y11 T13 K15 R16 P17 Y18 K36 N37 K38 K39 Y42 R43 K50 E71 A74 R77 R78 R81 K119 S120 H123 Q130 R131 H132 Q138 I142 F145 R148 P162 R167 P168 G169 R170 V171 A172 N175

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003723 RNA binding GO:0003735 structural constituent of ribosome GO:0005515 protein binding GO:0019843 rRNA binding

	Biological Process
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364	rRNA processing
GO:0006412	translation
GO:0042254	ribosome biogenesis
GO:0042274	ribosomal small subunit biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:0030686	90S preribosome
GO:0032040	small-subunit processome
GO:0043226	organelle
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component