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Structure of PDB 4v6g Chain DX Binding Site BS01

Receptor Information >4v6g Chain DX (length=59) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] PRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVA HLVRVEVVE

Ligand information >4v6g Chain DA (length=2886) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] agaugguaagggcccacgguggaugccucggcacccgagccgaugaagga cguggcuaccugcgauaagccagggggagccgguagcgggcguggauccc uggauguccgaaugggggaacccggccggcgggaacgccggucaccgcgc uuuuugcgcggggggaaccuggggaacugaaacaucucaguacccagagg agaggaaagagaaaucgacucccugaguagcggcgagcgaaaggggacca gccuaaaccguccggcuuguccgggcggggucguggggcccucggacacc gaauccccagccuagccgaagcuguugggaagcagcgccagagaggguga aagccccguaggcgaaagguggggggauaggugaggguacccgaguaccc cgugguucguggagccaugggggaaucugggcggaccaccgccuaaggcu aaguacuccgggugaccgauagcgcaccaguaccgugagggaaaggugaa aagaaccccgggaggggagugaaauagagccugaaaccgugggcuuacaa gcagucacggccccgcaagggguuguggcgugccuauugaagcaugagcc ggcgacucacggucgugggcgagcuuaagccguugaggcggaggcguagg gaaaccgaguccgaacagggcgcaaacgaaaaguccgcggccguggaccc gaaaccgggcgagcuagcccuggccagggugaagcuggggugagacccag uggaggcccgaaccggugggggaugcaaaccccucggaugagcuggggcu aggagugaaaagcuaaccgagcccggagauagcugguucuccccgaaaug acuuuagggucagccucaggcgcugacuggggccuguagagcacugauag ggcuagggggcccaccagccuaccaaacccugucaaacuccgaagggucc cagguggagccugggagugagggcgcgagcgauaacguccgcguccgagc gcgggaacaaccgagaccgccagcuaaggcccccaagucugggcuaagug guaaaggauguggcgccgcgaagacagccaggauguuggcuuagaagcag ccaucauuuaaagagugcguaauagcucacuggucgaguggcgccgcgcc gaaaaugaucggggcuuaagcccagcgccgaagcugcgggucugggggau gaccccaggcgguaggggagcguucccgaugccgaugaaggccgacccgc gagggcggcuggagguaagggaagugcgaaugccggcaugaguaacgaua aagagggugagaaucccucucgccguaagcccaaggguuccuacgcaaug gucgucagcguaggguuaggcgggaccuaaggugaagccgaaaggcguag ccgaagggcagccgguuaauauuccggcccuucccgcaggugcgaugggg ggacgcucuaggcuagggggaccggagccauggacgagcccggccagaag cgcagggugggagguaggcaaauccgccucccaacaagcucugcguggug gggaagcccguacgggugacaaccccccgaagccagggagccaagaaaag ccucuaagcacaaccugcgggaacccguaccgcaaaccgacacagguggg cgggugcaagagcacucaggcgcgcgggagaacccucgccaaggaacucu gcaaguuggccccguaacuucgggagaaggggugcucccuggggugauga gccccggggagccgcagugaacaggcucuggcgacuguuuaccaaaaaca cagcucucugcgaacucguaagaggagguauagggagcgacgcuugcccg gugccggaaggucaaggggaggggugcaagccccgaaccgaagccccggu gaacggcggccguaacuauaacgguccuaagguagcgaaauuccuugucg gguaaguuccgaccugcacgaaaagcguaacgaccggagcgcugucucgg cgagggacccggugaaauugaacuggccgugaagaugcggccuacccgug gcaggacgaaaagaccccguggagcuuuacugcagccugguguuggcucu uggucgcgccugcguaggauaggugggagccugugaacccccgccuccgg gugggggggaggcgccggugaaauaccacccuggcgcggcugggggccua acccucggauggggggacagcgcuuggcgggcaguuugacuggggcgguc gccuccuaaaagguaacggaggcgcccaaagguccccucaggcgggacgg aaauccgccggagagcgcaaggguagaagggggccugacugcgaggccug caagccgagcaggggcgaaagccgggccuagugaaccgguggucccgugu ggaagggccaucgaucaacggauaaaaguuaccccggggauaacaggcug aucucccccgagcguccacagcggcggggagguuuggcaccucgaugucg gcucgucgcauccuggggcugaagaaggucccaaggguugggcuguucgc ccauuaaagcggcacgcgagcuggguucagaacgucgugagacaguucgg ucucuauccgccacgggcgcaggaggcuugaggggggcucuuccuaguac gagaggaccggaagggacgcaccucugguuucccagcugucccuccaggg gcauaagcuggguagccaugugcggaagggauaaccgcugaaagcaucua agcgggaagcccgccccaagaugaggccucccacggcgucaagccgguaa ggacccgggaagaccacccgguggaugggccggggguguaagcgccgcga ggcguugagccgaccggucccaaucguccgaggucu <<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<< <<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>> >>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<<< .....>>>>>>.>>...<<<<<<.....<......>......>>>>>.>. ........<<....>>...<<<<<.....<<.....>>....>>>>>... <<<....<<<<<<<<.....>>>>>>>>......<<<<<<<<<....<<< ...<<<<<.<<<<.<<<...<<<<<......>>>>>((......<<<... ..))>>>...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....<<< <<<<<<.......>>>>>>>>>......<<<<<..((((>>>>>..>>>. .....>>.>>>>>>.>>...............<<....>>....>>.... .....<<<<....>>>>..................>>>>>>>>>>>.... ...<<<<<<<<<<<....>>>>>>>>>>>...<.<........>.>.<<< <<<....<<<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<< ....>>..<<<<.....>>>>...........>>>>>>>>>>>>>..<<. <...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>> >.....>>>...<<<..<<<<........>>>>.>>>....>>>>>>>>> ...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<< <<<....>>>>><<<<<<<<<.....<<<<<<<<<...<<<...<<<<<< <<.<.<<<<<<......>>>>.>>.>.>>>>>>>>..>>.>...>>>>>> >>>.....>>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>.... .<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<...... .....<<..<<<<<<<<<........<<<<<.<<...<<<<.......>> >>...>>.........<<......>>...>>>>>....>>>>>>>>>.>> ..........)))......>>>>>>.>>>...>>>>>>><<<<<<<<... ..>>>>>>>>....>>>>>><.<<<<<...<<<......<<<<<.<<<.. ..>>>>>>>>...>>>..>>>>>..>.....>>>>>><......<<.... .<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<< .....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...> >>...>>...<<<<<........>>>>>))<<<<<<<<<<<<<...<<<< ....<<<<<.<<<..<<<<<.<<<<.<<..[[[....>>>>>><<<...< <<<<<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>>>>>>..>> ><...<<<<....>>>>.....>>>>>>...>>>..>>>>>......... >>>>...>>...>>>>>>>>>>>>>>>..>>.....<<......>>>>>> >.<<<<<....>>>>>..>>>>..<<<<....<<<<<<<<.<<<...... ..<.....<<<<<.....<..>......>>>>><<<<<<<<<<<<..... >>>>>>>>>>>>............<<<<<<<<<..<<<.........>>> ..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<.. <<<<<<<..<<<...<<...<<<<<....>>>>>...>>...>>>>>>>> ..>>>>><<<<<<.......>>>>>>........<...........<<<< <<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..>.>>>.>> >>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<< <<.<<<.........<<<<.<<<<<<..<<<<<.<<<.<<<<<.<<<<<< <<<<<<<<<<...........<<<<<..<<<......<<<<<<<<....> >>>>>>>...>>>............>>>>>..>>>>>>>>>>>>>>>>.. .<<<<<....>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>>> <<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.... ...>>>>>>.....<<...(((>>....>>>>>>>...<<<<..<<<... ...>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.<<..)) ))..>>>>>>>>>.............>>>>..>>>>>>.......<<<<. <.<<<<<<<..<<.......>>>..>>>>>>...>>>>.>.......<.< <<.<<<<<<..<<<<<<<<<......>>>>>>>..>>.<<<<<.....>> >>>.....>>>>>..>...>>>..>....<<<<<<<....>>>.>>>>.. ......>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<...... .........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.]]]>>> >>>...>>>>>...>>>>.>>>>>...<<<....<<<<<........... >>>>>....>>>.>>>>.......>>>>>>>...<<<.....>>>..... <<<<<<<<<.......>>>>>....<<<<<<<<.<<<....<<<<<.... >>>>>...>>>..>>>>>.>>>...>>>>....>>>

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 4v6g Structural aspects of messenger RNA reading frame maintenance by the ribosome. Resolution 3.5 Å Binding residue (original residue number in PDB) K10 S11 I13 G14 Y15 K17 D18 A21 A22 K24 R29 R30 L31 Q32 P41 A42 G45 N46 K49 Binding residue (residue number reindexed from 1) K9 S10 I12 G13 Y14 K16 D17 A20 A21 K23 R28 R29 L30 Q31 P40 A41 G44 N45 K48

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003735 structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015934	large ribosomal subunit
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component