Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

Structure of PDB 4wzo Chain J5 Binding Site BS01

Receptor Information >4wzo Chain J5 (length=56) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] AKHPVPKKKTSKARRDARRSHHALTPPTLVPCPECKAMKPPHTVCPECGY YAGRKV

Ligand information >4wzo Chain 14 (length=2877) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] aagaugguaagggcccacgguggaugccucggcacccgagccgaugaagg acguggcuaccugcgauaagccagggggagccgguagcgggcguggaucc cuggauguccgaaugggggaacccggccggcgggaacgccggucaccgcg cuugcgcggggggaaccuggggaacugaaacaucucaguacccagaggag aggaaagagaaaucgacucccugaguagcggcgagcgaaaggggaccagc cuaaaccguccggcuuguccgggcggggucguggggcccucggacaccga auccccagccuagccgaagcuguugggaagcagcgccagagagggugaaa gccccguaggcgaaagguggggggauaggugaggguacccgaguaccccg ugguucguggagccaugggggaaucugggcggaccaccgccuaaggcuaa guacuccgggugaccgauagcgcaccaguaccgugagggaaaggugaaaa gaaccccgggaggggagugaaauagagccugaaaccgugggcuuacaagc agucacggccccgcaagggguuguggcgugccuauugaagcaugagccgg cgacucacggucgugggcgagcuuaagccguugaggcggaggcguaggga aaccgaguccgaacagggcgcaaacggcccgcacgcgggccgaaaagucc gcggccguggacccgaaaccgggcgagcuagcccuggccagggugaagcu ggggugagacccaguggaggcccgaaccggugggggaugcaaaccccucg gaugagcuggggcuaggagugaaaagcuaaccgagcccggagauagcugg uucuccccgaaaugacuuuagggucagccucaggcgcugacuggggccug uagagcacugauagggcuagggggcccaccagccuaccaaacccugucaa acuccgaagggucccagguggagccugggagugagggcgcgagcgauaac guccgcguccgagcgcgggaacaaccgagaccgccagcuaaggcccccaa gucugggcuaagugguaaaggauguggcgccgcgaagacagccaggaugu uggcuuagaagcagccugcguaauagcucacuggucgaguggcgccgcgc cgaaaaugaucggggcuuaagcccagcgccgaagcugcgggucuggggga ugaccccaggcgguaggggagcguucccgaugccgaugaaggccgacccg cgagggcggcuggagguaagggaagugcgaaugccggcaugaguaacgau aaagagggugagaaucccucucgccguaagcccaaggguuccuacgcaau ggucgucagcguaggguuaggcgggaccuaaggugaagccgaaaggcgua gccgaagggcagccgguuaauauuccggcccuucccgcaggugcgauggg gggacgcucuaggcuagggggaccggagccauggacgagcccggccagaa gcgcagggugggagguaggcaaauccgccucccaacaagcucugcguggu ggggaagcccguacgggugacaaccccccgaagccagggagccaagaaaa gccucuaagcacaaccugcgggaacccguaccgcaaaccgacacaggugg gcgggugcaagagcacucaggcgcgcgggagaacccucgccaaggaacuc ugcaaguuggccccguaacuucgggagaaggggugcucccuggggugaug agccccggggagccgcagugaacaggcucuggcgacuguuuaccaaaaac acagcucucugcgaacucguaagaggagguauagggagcgacgcuugccc ggugccggaaggucaaggggaggggugcaagccccgaaccgaagccccgg ugaacggcggccguaacuauaacgguccuaagguagcgaaauuccuuguc ggguaaguuccgaccugcacgaaaagcguaacgaccggagcgcugucucg gcgagggacccggugaaauugaacuggccgugaagaugcggccuacccgu ggcaggacgaaaagaccccguggagcuuuacugcagccugguguuggcuc uuggucgcgccugcguaggauaggugggagccugugaacccccgccuccg ggugggggggaggcgccggugaaauaccacccuggcgcggcugggggccu aacccucggauggggggacagcgcuuggcgggcaguuugacuggggcggu cgccuccuaaaagguaacggaggcgcccaaagguccccucaggcgggacg gaaauccgccggagagcgcaaggguagaagggggccugacugcgaggccu gcaagccgagcaggggcgaaagccgggccuagugaaccgguggucccgug uggaagggccaucgaucaacggauaaaaguuaccccggggauaacaggcu gaucucccccgagcguccacagcggcggggagguuuggcaccucgauguc ggcucgucgcauccuggggcugaagaaggucccaaggguugggcuguucg cccauuaaagcggcacgcgagcuggguucagaacgucgugagacaguucg gucucuauccgccacgggcgcaggaggcuugaggggggcucuuccuagua cgagaggaccggaagggacgcaccucugguuucccagcugucccuccagg ggcauaagcuggguagccaugugcggaagggauaaccgcugaaagcaucu aagcgggaagcccgccccaagaugaggccucccacgccgguaaggacccg ggaagaccacccgguggaugggccggggguguaagcgccgcgaggcguug agccgaccggucccaaucguccgaggu ..........<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<< <<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>> >>>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<< <..>>>>>>.>>....<<<<<.....<......>......>>>>>..... ......<<....>>...<<<<<.....<<.....>>....>>>>>...<< <....<<<<<<<<.....>>>>>>>>......<<<<<<<<<....<<<.. .<<<<<.<<<<.<<<...<<<<<......>>>>>((......<<<..... ))>>>...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....<<<<< <<<<.......>>>>>>>>>......<<<<<..((((>>>>>..>>>... ...>>.>>>>>>.>>...............<<....>>....>>...... ...<<<<....>>>>..................>>>>>>>>>>>...... .<<<<<<<<<<<....>>>>>>>>>>>...<............>.<<<<< <....<<<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<<.. ..>>..<<<<.....>>>>..........<......>.........>>>> >>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<....<<< <<<......>>>>>>.....>>>...<<<..<<<<........>>>>.>> >....>>>>>>>>>...<<<.....>>>......>>>>>>......>.>> ..<<<<<<....<<<<<....>>>>><<<<<<<<<.....<<<<<<<<<. ..<<<...<<<<<<<<....<<<<<......>>>>.>....>>>>>>>>. .>>.>...>>>>>>>>>.....>>>>>>>.>>..<<<<<<<.<<...... >>.>>>>>>>.....<<<......>>>...<<<<.<<<...<<<(((... ..<<<<<<...........<<..<<<<<<<<<......<.<<<<<..... .................<<......>>...>>>>>.>..>>>>>>>>>.> >..........)))......>>>>>>.>>>...>>>>>>><<<<<<<<.. ...>>>>>>>>....>>>>>><.<<<<<...<<<......<<<<<.<<<. ...>>>>>>>>...>>>..>>>>>..>.....>>>>>><......<<... ..<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...< <.....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>... >>>...>>...<<<<<........>>>>>))<<<<<<<<<<<<<...<<< <....<<<<<.<<<..<<<<<.<<<<.<<..[[[[...>>>>>><<<... <<<<<<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>>>>>>..> >><...<<<<....>>>>.....>>>>>>...>>>..>>>>>........ .>>>>...>>...>>>>>>>>>>>>>>>..>>.....<<......>>>>> >>.<<<<<....>>>>>..>>>>..<<<<....<<<<<<<<.<<...... ...<.....<<<<<...............>>>>><<<<<<<<<<<<.... .>>>>>>>>>>>>............<<<<<<<<<..<<<.........>> >..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.<<<. .<<<<<<<..<<<...<<...<<<<<....>>>>>...>>...>>>>>>> >..>>>>><<<<<<.......>>>>>>........<...........<<< <<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.> >>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<< <<<.<<<.........<<<<.<<<<<<..<<<<<.<<<.<<<<<.<<<<< <<<<<<<<<<<...........<<<<<..<<<......<<<<<<<<.... >>>>>>>>...>>>............>>>>>..>>>>>>>>>>>>>>>>. ..<<<<<....>>>>>....>>>>>.>>>..>>>>>..<<<<.....>>> ><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<... ....>>>>>>.....<<...(((>>....>>>>>>>...<<<<..<<<.. ....>>>..>>>>.<<<....>>>.>>))).......<<<<<<<.<<..) )))..>>>>>>>>>.............>>>>..>>>>>>.......<<<< ..<<<<<<<...<<.......>>...>>>>>>>...>>>.>.......<< <<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....> >>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>. .......>>>>>>>>>>>....<<<<<<<...<<<<..<<<<<<<..... ..........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<]]]]>> >>>>...>>>>>...>>>>.>>>>>...<<<....<<<<........... ..>>>>....>>>.>>>>.......>>>>>>>..<<.>>....<<<<<<< <<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>.. .>>>..>>>>>.>>>...>>>>.....

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 4wzo Structural insights into the translational infidelity mechanism. Resolution 3.3 Å Binding residue (original residue number in PDB) A2 K3 H4 P5 V6 P7 K8 K9 K10 T11 S12 K13 A14 R15 R16 D17 A18 R19 R20 S21 H22 H23 T29 V31 P32 P34 H43 Y52 Binding residue (residue number reindexed from 1) A1 K2 H3 P4 V5 P6 K7 K8 K9 T10 S11 K12 A13 R14 R15 D16 A17 R18 R19 S20 H21 H22 T28 V30 P31 P33 H42 Y51

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003735 structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015934	large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component