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Structure of PDB 7syi Chain a Binding Site BS01

Receptor Information >7syi Chain a (length=77) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] KVRDKLNNLVLFDKATYDKLCKEVPNYKLITPAVVSERLKIRGSLARAAL QELLSKGLIKLVSKHRAQVIYTRNTKG

Ligand information >7syi Chain 2 (length=1697) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau uaaaucaguuaugguuccuuuggucgcucgacuuggauaacugugguaau ucuagagcuaauacaugccgacgggcgcugacccccuucgcgggggggau gcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgc ccggcggcgacgacccauucgaacgucugcccuaucaacuuucgauggua gucgccgugccuaccauggugaccacgggugacggggaaucaggguucga uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca ggcgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaa caauacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaa uccuuuaacgaggauccauuggagggcaagucuggugccagcagccgcgg uaauuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcuc guaguuggaucuugggagcggccguccccugcucggcgccggcccgaagc guuuacuuugaaaaaauuagaguguucaaagcaggccgccuggauaccgc agcuaggaauaauggaauaggaccgcgguucuauuuuguugguuuucgga acugaggccaugauuaagagggacggccgggggcauucguauugcgccgc uagaggugaaauucuuggaccggcgcaagacggaccagagcgaaagcauu ugccaagaauguuuucauuaaucaagaacgaaagucggagguucgaagac gaucagauaccgucguaguuccgaccauaaacgaugccgaccggcgaugc ggcggcguuauucccaugacccgccgggcagcuuccgggaaaccaaaguc uuuggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauuu ggcgaagggcaccaccaggaguggagccugcggcuuaauuugacucaaca cgggaaaccucacccggcccggacacggacaggauugacagauugauagc ucuuucucgauuccgugggugguggugcauggccguucuuaguuggugga gcgauuugucugguuaauuccgauaacgaacgagacucuggcaugcuaac uaguuacgcgaccccggucggcguaacuucuuagagggacaaguggcguu cagccacccgagauugagcaauaacaggucugugaugcccuuagaugucc ggggcugcacgcgcgcuacacugacuggcucagcgugugccuacccuacg ccggcaggcgcggguaacccguugaaccccauucgugauggggaucgggg auugcaauuauuccccaugaacgaggaauucccaguaagugcgggucaua agcuugcguugauuaagucccugcccuuuguacacaccgcccgucgcuac uaccgauuggaugguuuagugaggcccucggaucggccccgccggggugc ccuggcggagcgcugagaagacggucgaacuugacuaucuagaggaagua aaagucguaacaagguuuccguaggugaaccugcggaaggaucauua ...<<<<<.[[((((>>>>><<<.<<<<<<...<.<<..<......<<<. <<<..<<....<<....<<..........>>...>>.>>......<<... .....<<<.<....<<....<<<<<........<<.....<<..<..... ..>..>>......>>.........<<<<...<<<<<<....>>>>>>... >>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<< <.>>>>>>>>.>>.>>>...>>..>.>>>.<<<....<<<.....<<<<< <.........>>>>>>.>>>......>>>...<<<.<<<<....>>>>.. ..>>>.>>.<<.<<<..........>>>.>>...<<<..>>>.....>>> >>>.........<<<...<<<<.....>>>.>>>>..>...>>.>..... <<<.<<<<<.<<......>>..>>>>>..>>>......<...<....... ....>...>.........<<<<<((......<<<<.....<<..))>>.. .....>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.<< ...<<<.<<....<<<.<<<..>>>.>>>.<<<<...<<..>>..>>.>> ..<<<<<<.<.......<<...<.......>.<<<<.>>>>...>>.... ..>.>>>..>>>........<.<<.<<<<<<<...............>>> >>>>.>>.>....>>....<<<<<<......<<<<..<<..<<<<<<<<. ..<<<......>>>......>>>>>>>>..>>.......<<....>>... >>>>.....>>>.>>>...>>>...>>.>....<<<<<<....<...<<< <.<.....>.>>>>...>.>>>>>>..........<<<.<<.<<<..<.< <<<<<.<<<........>>>>>>>>>.>..>>>...<<..))>>...>>. ....>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]]. <...<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........ >>..........<<<<<......<<<<<<.......<<.<<<........ >>>.>>.....>>>>>>...<<.<<<..<..<<<<<.....<<<.<<<<. .....>>...<<<......>>>...>>.>>>....<<<...<...<.<<. .<<<<<<<<<<<<..>>>>.>>>>>>>>..>>.>..>.....<<<<<... ..>>>>>........>>>.....>>.>>>......>>>>>>.......>> >>>...>>.>>>>.>>>.....<<.<<<................<<<.<< <<....>>>>.>>>..............>>>.>>......<.....<<<< <..........>>>>>.....>.....>>>>>.....<<<<<<<<..... ..>>>>>>>>......>>...>>>>>>>..>.......<...<.<..<<< <.<<....<<<<<<<<.<<<...<<<.<<...<<<<<..<<<<.<<<..> >>.>>>>....>>>>>...>>.>>>...>>>.>>>>>>>>...>>.>>>> ...>.>....>.....<<<<<<<<<....>>>>>>>>>.........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 7syi Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Resolution 4.5 Å Binding residue (original residue number in PDB) K43 L44 N45 N46 R80 G81 S82 R85 K102 R104 Binding residue (residue number reindexed from 1) K5 L6 N7 N8 R42 G43 S44 R47 K64 R66

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003735 structural constituent of ribosome

	Biological Process
GO:0006364	rRNA processing
GO:0042274	ribosomal small subunit biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005840	ribosome
GO:0014069	postsynaptic density
GO:0022626	cytosolic ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:0045202	synapse
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component