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Structure of PDB 8g5y Chain LF Binding Site BS02

Receptor Information >8g5y Chain LF (length=225) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] NFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKEYRQMYRTEIRMAR MARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFV KLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNA LIARSLGKYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKK TTHFVEGGDAGNREDQINRLIRRMN

Ligand information >8g5y Chain L7 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga auaccgggugcuguaggcuu <<<<<<<<<....<<<<<<<<.....<<<<<..............>>>.. >>....>>>>>>.>><<<<<<<.....<<.<<..<<....>>.>>.>>.. ..>>>>>>>>>>>>>>>>..

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8g5y mRNA decoding in human is kinetically and structurally distinct from bacteria. Resolution 2.29 Å Binding residue (original residue number in PDB) R134 E137 K222 T224 T225 H226 E229 Binding residue (residue number reindexed from 1) R111 E114 K199 T201 T202 H203 E206

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003723 RNA binding GO:0003729 mRNA binding GO:0003735 structural constituent of ribosome GO:0005515 protein binding GO:0042802 identical protein binding

	Biological Process
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181	cytoplasmic translation
GO:0006364	rRNA processing
GO:0006412	translation
GO:0042273	ribosomal large subunit biogenesis

	Cellular Component
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0005925	focal adhesion
GO:0014069	postsynaptic density
GO:0016020	membrane
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:1990904	ribonucleoprotein complex

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