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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

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Structure of PDB 7ksz Chain A Binding Site BS04

Receptor Information >7ksz Chain A (length=325) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] MPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLTFCRAASVLK ALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSERYQTM KLFTQIFGVGVKTADRWYREGLRTLDDLREQPQKLTQQQKAGLQHHQDLS TPVLRSDVDALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITH PKEGQEAGLLPRVMCRLQDQGLILYHQFERSFCIFRLPQPGSWKAVRVDL VVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQKTF FQAASEEDIFRHLGLEYLPPEQRNA

Ligand information Ligand ID CA InChI InChI=1S/Ca/q+2 InChIKey BHPQYMZQTOCNFJ-UHFFFAOYSA-N SMILES Software SMILES CACTVS 3.341 [Ca++] ACDLabs 10.04 OpenEye OEToolkits 1.5.0 [Ca+2] Formula Ca Name CALCIUM ION ChEMBL DrugBank DB14577 ZINC PDB chain 7ksz Chain A Residue 507 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 7ksz Watching a double strand break repair polymerase insert a pro-mutagenic oxidized nucleotide. Resolution 1.417 Å Binding residue (original residue number in PDB) D330 D332 Binding residue (residue number reindexed from 1) D193 D195 Annotation score 1

Enzymatic activity Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003887 DNA-directed DNA polymerase activity GO:0016779 nucleotidyltransferase activity GO:0034061 DNA polymerase activity

	Biological Process
GO:0006281	DNA repair

	Cellular Component
GO:0005634	nucleus

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