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Structure of PDB 7sz8 Chain B Binding Site BS07

Receptor Information >7sz8 Chain B (length=416) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] DVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVD FPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSSSTSVSITV LDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDANSVITYQLTGG NTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDGTRSHTAHVLI NVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYV IQDPVPQFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTT LEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRL LYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPT PLSASVEIQVTILDIN

Ligand information Ligand ID CA InChI InChI=1S/Ca/q+2 InChIKey BHPQYMZQTOCNFJ-UHFFFAOYSA-N SMILES Software SMILES CACTVS 3.341 [Ca++] ACDLabs 10.04 OpenEye OEToolkits 1.5.0 [Ca+2] Formula Ca Name CALCIUM ION ChEMBL DrugBank DB14577 ZINC PDB chain 7sz8 Chain B Residue 808 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 7sz8 Crystal structure of human CELSR1 EC4-7 Resolution 2.337 Å Binding residue (original residue number in PDB) E565 D616 E618 D652 Binding residue (residue number reindexed from 1) E223 D274 E276 D310 Annotation score 4

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0005509 calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609	cell-cell adhesion

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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