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BioLiP

Structure of PDB 6hon Chain A

Receptor sequence
>6honA (length=271) Species: 9606 (Homo sapiens) [Search protein sequence]
HMLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGTIA
ALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLAAH
IPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTEII
PLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMILG
KMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTFAQ
VLKDDTTTKRWLAQLVKNLQE
3D structure
PDB6hon A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R46 A84 H85 S87 N88 C91 N92 Y134 L137 T138 L177 T180 V181 F184 R227 H231 R32 A70 H71 S73 N74 C77 N78 Y120 L123 T124 L163 T166 V167 F170 R213 H217
Gene Ontology
Biological Process
GO:0006402 mRNA catabolic process
Cellular Component
GO:0030014 CCR4-NOT complex

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Biological Process
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Cellular Component
External links
PDB RCSB:6hon, PDBe:6hon, PDBj:6hon
PDBsum6hon
PubMed30692204
UniProtQ92600|CNOT9_HUMAN CCR4-NOT transcription complex subunit 9 (Gene Name=CNOT9)

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