Structure of PDB 8trq Chain A

Receptor sequence

>8trqA (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]

EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEFDT

3D structure

PDB

8trq T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4

Chain

Resolution

2.75 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Q9 A52 S53 F54 N62 V65 D66 N69 I72 M73	Q7 A50 S51 F52 N60 V63 D64 N67 I70 M71

External links

PDB	RCSB:8trq, PDBe:8trq, PDBj:8trq
PDBsum	8trq
PubMed	39043656
UniProt	P01903\|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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