Structure of PDB 5tix Chain B

Receptor sequence

>5tixB (length=246) Species: 6185 (Schistosoma haematobium) [Search protein sequence]

TTIQVIGAGLPRTGTNSMKKALEIIYSKPCYHMYEIIFKKQSDISIWQQL
IDETHKTTSDKRKIYNGLNELLNGYIATTDLPSCSFYKELMTMYPNAKVL
LTIRDKYDWLYSLRKVVLPKSTDPWKLKIEEGDQVLGIDSNFYKMSEDSL
KFAFQKNHINLDDDEILLECYDEYNRLVQEIVPPERLLIHHLGDGWESLC
QFLNVDIPNGISYPCANSHHQMTQLTEQLIKHKSLDDIIHMFPGLI

3D structure

PDB

5tix Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy.

Chain

Resolution

1.78 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	A3P	B	R32 G34 T35 N36 S37 R124 S132 L212 C235 N237 S238 H239	R12 G14 T15 N16 S17 R104 S112 L192 C215 N217 S218 H219
BS02	OQR	B	I57 L101 V137 D153 F162 S166	I37 L81 V117 D133 F142 S146

Gene Ontology

	Molecular Function
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:5tix, PDBe:5tix, PDBj:5tix
PDBsum	5tix
PubMed	28536265
UniProt	A0A094ZWQ2

[Back to BioLiP]

zhanglab

zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417