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Name | P2Y purinoceptor 2 |
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Species | Homo sapiens (Human) |
Gene | P2RY2 |
Synonym | Purinergic receptor purinergic receptor P2Y P2Y2 receptor P2Y2 P2Y purinoceptor 2 [ Show all ] |
Disease | Dry eye disease Constipation Cystic fibrosis Lung cancer |
Length | 377 |
Amino acid sequence | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL |
UniProt | P41231 |
Protein Data Bank | N/A |
GPCR-HGmod model | P41231 |
3D structure model | This predicted structure model is from GPCR-EXP P41231. |
BioLiP | N/A |
Therapeutic Target Database | T93515 |
ChEMBL | CHEMBL4398 |
IUPHAR | 324 |
DrugBank | BE0002401 |
Name | CHEMBL1672106 |
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Molecular formula | C23H15N6NaO7S |
IUPAC name | sodium;1-amino-4-[4-[(4,6-dioxo-1H-1,3,5-triazin-2-yl)amino]anilino]-9,10-dioxoanthracene-2-sulfonate |
Molecular weight | 542.458 |
Hydrogen bond acceptor | 9 |
Hydrogen bond donor | 5 |
XlogP | None |
Synonyms | N/A |
Inchi Key | GJMBLLXANUDGDH-UHFFFAOYSA-M |
Inchi ID | InChI=1S/C23H16N6O7S.Na/c24-18-15(37(34,35)36)9-14(16-17(18)20(31)13-4-2-1-3-12(13)19(16)30)25-10-5-7-11(8-6-10)26-21-27-22(32)29-23(33)28-21;/h1-9,25H,24H2,(H,34,35,36)(H3,26,27,28,29,32,33);/q;+1/p-1 |
PubChem CID | 53326684 |
ChEMBL | CHEMBL1672106 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
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IC50 | 30000.0 nM | PMID21207957 | ChEMBL |
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