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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL216047
Molecular formula	C31H33Cl2N5O
IUPAC name	2-chloro-N-[3-chloro-6-[4-(cyclohexylmethyl)piperazin-1-yl]benzo[b][1,4]benzodiazepin-11-yl]benzamide
Molecular weight	562.539
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	7.4
Synonyms	BDBM50190096 2-chloro-N-[8-chloro-11-(4-cyclohexylmethyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-benzamide
Inchi Key	AQYOBQIIGLFQRP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H33Cl2N5O/c32-23-14-15-29-27(20-23)34-30(37-18-16-36(17-19-37)21-22-8-2-1-3-9-22)25-11-5-7-13-28(25)38(29)35-31(39)24-10-4-6-12-26(24)33/h4-7,10-15,20,22H,1-3,8-9,16-19,21H2,(H,35,39)
PubChem CID	44415805
ChEMBL	CHEMBL216047
IUPHAR	N/A
BindingDB	50190096
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12212	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
12211	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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