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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL303993
Molecular formula	C16H16ClNO
IUPAC name	(1S)-6-chloro-2-methyl-1-phenyl-3,4-dihydro-1H-isoquinolin-7-ol
Molecular weight	273.76
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	3.8
Synonyms	(1S)-1alpha-Phenyl-2-methyl-6-chloro-1,2,3,4-tetrahydroisoquinolin-7-ol 6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol (S)-6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol BDBM50038349 ZINC13675794
Inchi Key	AVXGCGYACIYZAR-INIZCTEOSA-N
Inchi ID	InChI=1S/C16H16ClNO/c1-18-8-7-12-9-14(17)15(19)10-13(12)16(18)11-5-3-2-4-6-11/h2-6,9-10,16,19H,7-8H2,1H3/t16-/m0/s1
PubChem CID	10107367
ChEMBL	CHEMBL303993
IUPHAR	N/A
BindingDB	50038349
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15729	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
15730	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
15727	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
15728	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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