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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL194408
Molecular formula	C23H26Cl2N4O2
IUPAC name	2-(2,4-dichlorophenoxy)-N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methylquinolin-6-yl]acetamide
Molecular weight	461.387
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50172432 SCHEMBL5910434 2-(2,4-Dichloro-phenoxy)-N-{2-[(2-dimethylamino-ethyl)-methyl-amino]-4-methyl-quinolin-6-yl}-acetamide
Inchi Key	FWSBSBDRADXORX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26Cl2N4O2/c1-15-11-22(29(4)10-9-28(2)3)27-20-7-6-17(13-18(15)20)26-23(30)14-31-21-8-5-16(24)12-19(21)25/h5-8,11-13H,9-10,14H2,1-4H3,(H,26,30)
PubChem CID	11512135
ChEMBL	CHEMBL194408
IUPHAR	N/A
BindingDB	50172432
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
89178	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
89179	Melanin-concentrating hormone receptor 2	Q969V1	MCHR2	Homo sapiens (Human)	340

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