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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL121744
Molecular formula	C24H27N3O2
IUPAC name	2-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-1,2,3,9-tetrahydrocarbazol-4-one
Molecular weight	389.499
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.7
Synonyms	BDBM50403682 2-[4-(2-Methoxyphenyl)piperazinomethyl]-1,2-dihydro-9H-carbazole-4(3H)-one
Inchi Key	IHQJQJGQVPNKSI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H27N3O2/c1-29-23-9-5-4-8-21(23)27-12-10-26(11-13-27)16-17-14-20-24(22(28)15-17)18-6-2-3-7-19(18)25-20/h2-9,17,25H,10-16H2,1H3
PubChem CID	10715378
ChEMBL	CHEMBL121744
IUPHAR	N/A
BindingDB	50403682
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
133476	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
133474	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
133475	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
133477	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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