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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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GPCR

Name	P2Y purinoceptor 2
Species	Mus musculus (Mouse)
Gene	P2ry2
Synonym	Purinergic receptor P2Y2 receptor P2Y2 P2Y purinoceptor 2 ATP receptor P2Y ATP receptor 2 P2U1 P2U purinoceptor 1 purinergic receptor P2Y [ Show all ]
Disease	N/A for non-human GPCRs
Length	373
Amino acid sequence	MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL
UniProt	P35383
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075298
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL575202
Molecular formula	C7H11N2O7P
IUPAC name	2-[(2,4-dioxopyrimidin-1-yl)methoxy]ethyl dihydrogen phosphate
Molecular weight	266.146
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	-2.6
Synonyms	BDBM50378131
Inchi Key	QQXODIYVVBVZDS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C7H11N2O7P/c10-6-1-2-9(7(11)8-6)5-15-3-4-16-17(12,13)14/h1-2H,3-5H2,(H,8,10,11)(H2,12,13,14)
PubChem CID	45481630
ChEMBL	CHEMBL575202
IUPHAR	N/A
BindingDB	50378131
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<500000.0 nM	PMID19523835	BindingDB,ChEMBL
Inhibition	16.0 %	PMID19523835	ChEMBL

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