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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-2 adrenergic receptor
Species	Canis lupus familiaris (Dog)
Gene	ADRB2
Synonym	Beta-2 adrenoceptor Beta-2 adrenoreceptor
Disease	N/A for non-human GPCRs
Length	415
Amino acid sequence	MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
UniProt	P54833
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2289
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL351183
Molecular formula	C18H24N4O2S
IUPAC name	N-[4-[(1-phenylpiperazin-2-yl)methylamino]phenyl]methanesulfonamide
Molecular weight	360.476
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	2.1
Synonyms	N-[4-[[(1-Phenylpiperazin-2-yl)methyl]amino]phenyl]methanesulfonamide AFYXROQLTFFXOK-UHFFFAOYSA-N N-{4-[(1-Phenyl-piperazin-2-ylmethyl)-amino]-phenyl}-methanesulfonamide BDBM50001894 N-[4-[(1-Phenyl-2-piperazinyl)methylamino]phenyl]methanesulfonamide SCHEMBL9596252 [ Show all ]
Inchi Key	AFYXROQLTFFXOK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H24N4O2S/c1-25(23,24)21-16-9-7-15(8-10-16)20-14-18-13-19-11-12-22(18)17-5-3-2-4-6-17/h2-10,18-21H,11-14H2,1H3
PubChem CID	14998853
ChEMBL	CHEMBL351183
IUPHAR	N/A
BindingDB	50001894
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	42000.0 nM	PMID1347318	BindingDB,ChEMBL

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