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GPCR

Name	Olfactory receptor 5K1
Species	Homo sapiens (Human)
Gene	OR5K1
Synonym	HTPCRX10 Olfactory receptor OR3-8
Disease	N/A
Length	308
Amino acid sequence	MAEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHRRLHTPMYIFLGNLALVDSCCACAITPKMLENFFSENKRISLYECAVQFYFLCTVETADCFLLAAMAYDRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGSNHINHFYCDILPLYRLSCVDPYINELVLFIFSGSVQVFTIGSVLISYLYILLTIFKMKSKEGRAKAFSTCASHFLSVSLFYGSLFFMYVRPNLLEEGDKDIPAAILFTIVVPLLNPFIYSLRNREVISVLRKILMKK
UniProt	Q8NHB7
Protein Data Bank	N/A
GPCR-HGmod model	Q8NHB7
3D structure model	This predicted structure model is from GPCR-EXP Q8NHB7.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3721312
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	Kephalis
Molecular formula	C14H24O2
IUPAC name	4-(1-ethoxyethenyl)-3,3,5,5-tetramethylcyclohexan-1-one
Molecular weight	224.344
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	3.1
Synonyms	3,3,5,5-Tetramethyl-4-(1-ethoxyvinyl)cyclohexanone A823795 DTXSID6052039 4-(1-ethoxyethenyl)-3,3,5,5-tetramethyl-1-cyclohexanone ACM36306873 LS-57317 3,3,5,5-etramethyl-4-ethoxyvinylcyclohexanone 4-(1-Ethoxyethenyl)-3,3,5,5-tetramethylcyclohexanone CHEMBL3727737 ZINC5854083 3,3,5,5-Tetramethyl-4-ethoxyvinylcyclohexanone AC1L3MMQ EINECS 252-961-2 4-(1-ethoxyethenyl)-3,3,5,5-tetramethyl-cyclohexan-1-one BRN 2258311 SCHEMBL273630 3,3,5,5-Tetramethyl-4-(1-ethoxyvinyl)-1-cyclohexanone 4-(1-Ethoxyvinyl)-3,3,5,5-tetramethylcyclohexanone Cyclohexanone, 4-(1-ethoxyethenyl)-3,3,5,5-tetramethyl- 36306-87-3 AC1Q6EC1 4-(1-ethoxyethenyl)-3,3,5,5-tetramethylcyclohexan-1-one W-110874 [ Show all ]
Inchi Key	YLNYLLVKHRZLGO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H24O2/c1-7-16-10(2)12-13(3,4)8-11(15)9-14(12,5)6/h12H,2,7-9H2,1,3-6H3
PubChem CID	118292
ChEMBL	CHEMBL3727737
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Inhibition	50.0 %	None	ChEMBL

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