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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000066873
Molecular formula	C16H20N4O6
IUPAC name	[2-(4-amino-1-methyl-2,6-dioxo-3-propylpyrimidin-5-yl)-2-oxoethyl] 3,5-dimethyl-1,2-oxazole-4-carboxylate
Molecular weight	364.358
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	1.1
Synonyms	3,5-dimethylisoxazole-4-carboxylic acid [2-(4-amino-2,6-diketo-1-methyl-3-propyl-pyrimidin-5-yl)-2-keto-ethyl] ester cid_2115012 ZINC2651724 AKOS033943382 MLS000054929 2-(6-amino-3-methyl-2,4-dioxo-1-propyl-1,2,3,4-tetrahydropyrimidin-5-yl)-2-oxoethyl 3,5-dimethyl-1,2-oxazole-4-carboxylate 750603-06-6 HMS2279K19 [2-(4-amino-1-methyl-2,6-dioxo-3-propylpyrimidin-5-yl)-2-oxoethyl] 3,5-dimethyl-1,2-oxazole-4-carboxylate BDBM64914 MLS002635711 3,5-dimethyl-4-isoxazolecarboxylic acid [2-(4-amino-1-methyl-2,6-dioxo-3-propyl-5-pyrimidinyl)-2-oxoethyl] ester CHEMBL1545973 Z25519220 AC1M2D2O MCULE-5270705137 [2-[4-azanyl-1-methyl-2,6-bis(oxidanylidene)-3-propyl-pyrimidin-5-yl]-2-oxidanylidene-ethyl] 3,5-dimethyl-1,2-oxazole-4-carboxylate CHEBI:114925 MolPort-004-271-450 [ Show all ]
Inchi Key	AAHZIIKQJCMENQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H20N4O6/c1-5-6-20-13(17)12(14(22)19(4)16(20)24)10(21)7-25-15(23)11-8(2)18-26-9(11)3/h5-7,17H2,1-4H3
PubChem CID	2115012
ChEMBL	CHEMBL1545973
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
221	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757

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