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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001175729
Molecular formula	C28H31NO6
IUPAC name	methyl 4-[3-(6,7-dimethoxy-1-phenyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxypropoxy]benzoate
Molecular weight	477.557
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.3
Synonyms	877990-96-0 MolPort-004-151-469 CHEMBL1568451 methyl 4-[3-(6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinolin-2-yl)-2-hydroxypropoxy]benzoate AKOS033518246 SMR000595571 HMS2896O16 Z166614366 MCULE-6786640305 [ Show all ]
Inchi Key	ABROOOZQBGVEKG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H31NO6/c1-32-25-15-21-13-14-29(27(19-7-5-4-6-8-19)24(21)16-26(25)33-2)17-22(30)18-35-23-11-9-20(10-12-23)28(31)34-3/h4-12,15-16,22,27,30H,13-14,17-18H2,1-3H3
PubChem CID	16289403
ChEMBL	CHEMBL1568451
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1108	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463087	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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