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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Isoquinoline, 1,2,3,4-tetrahydro-2-(p-tolylsulfonyl)-
Molecular formula	C16H17NO2S
IUPAC name	2-(4-methylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline
Molecular weight	287.377
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.0
Synonyms	2-(4-methylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline AC1Q6U27 HMS1542P08 MolPort-000-557-499 SR-01000399575 2-[(4-Methylphenyl)sulfonyl]-1,2,3,4-tetrahydroisoquinoline BRD-K76147950-001-01-1 Isoquinoline, 1,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]- NSC124439 STK008628 ABXZGZXVLBYJDK-UHFFFAOYSA-N CTK4E3955 MCULE-8094726230 SCHEMBL13302259 2-(p-tolylsulfonyl)-1,2,3,4-Tetrahydro-isoquinoline AKOS000579719 HMS2829E08 N-tosyl-1,2,3,4-tetrahydroisoquinoline SR-01000399575-1 2-[(4-Methylphenyl)sulfonyl]-1,2,3,4-tetrahydroisoquinoline # Isoquinoline,2,3,4-tetrahydro-2-(p-tolylsulfonyl)- Oprea1_408863 TimTec1_003154 1,2,3,4-Tetrahydro-2-(p-tolylsulfonyl)isoquinoline AC1L5JVR DTXSID10298577 MLS001205087 SMR000515488 2-(Toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinoline BAS 00843752 NSC-124439 ST042473 20335-69-7 CHEMBL1327868 Isoquinoline,2,3,4-tetrahydro-2-[(4-methylphenyl)sulfonyl]- Oprea1_816059 ZINC29422 [ Show all ]
Inchi Key	ABXZGZXVLBYJDK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H17NO2S/c1-13-6-8-16(9-7-13)20(18,19)17-11-10-14-4-2-3-5-15(14)12-17/h2-9H,10-12H2,1H3
PubChem CID	276460
ChEMBL	CHEMBL1327868
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463114	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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