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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000046286
Molecular formula	C20H23N5O4S2
IUPAC name	2-[[4-ethyl-5-[(4-methylphenoxy)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(4-sulfamoylphenyl)acetamide
Molecular weight	461.555
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	1.9
Synonyms	AC1LDDFM MLS000083115 2-({4-ethyl-5-[(4-methylphenoxy)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)-N-(4-sulfamoylphenyl)acetamide C20H23N5O4S2 SCHEMBL18559237 STK591823 2-{[4-ethyl-5-(4-methylphenoxymethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(4-sulfamoylphenyl)acetamide HMS2301O08 AC1Q300J MLS002584025 2-[[4-ethyl-5-[(4-methylphenoxy)methyl]-1,2,4-triazol-3-yl]sulfanyl]-N-(4-sulfamoylphenyl)acetamide ZINC4295988 861140-30-9 MCULE-1932111955 AKOS005513991 MolPort-001-854-749 2-{4-ethyl-5-[(4-methylphenoxy)methyl](1,2,4-triazol-3-ylthio)}-N-(4-sulfamoyl phenyl)acetamide CHEMBL1383442 ST50417045 [ Show all ]
Inchi Key	ACRQEVCUBADABH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23N5O4S2/c1-3-25-18(12-29-16-8-4-14(2)5-9-16)23-24-20(25)30-13-19(26)22-15-6-10-17(11-7-15)31(21,27)28/h4-11H,3,12-13H2,1-2H3,(H,22,26)(H2,21,27,28)
PubChem CID	665270
ChEMBL	CHEMBL1383442
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463166	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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