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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000127728
Molecular formula	C22H22N4O
IUPAC name	1,5-bis(3,4-dimethylphenyl)-6-methylpyrazolo[3,4-d]pyrimidin-4-one
Molecular weight	358.445
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.2
Synonyms	AKOS001810149 HMS2252N10 MLS002586813 ZINC4971962 MCULE-1704171024 1,5-bis(3,4-dimethylphenyl)-6-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one MolPort-007-626-948 CHEMBL1308307 MLS000522461 [ Show all ]
Inchi Key	ACSYCUNAUJGSEE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22N4O/c1-13-6-8-18(10-15(13)3)25-17(5)24-21-20(22(25)27)12-23-26(21)19-9-7-14(2)16(4)11-19/h6-12H,1-5H3
PubChem CID	9550877
ChEMBL	CHEMBL1308307
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463171	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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