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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL397112
Molecular formula	C19H12ClF2NO2S
IUPAC name	2-[(E)-2-(2-chloro-4-fluorophenyl)ethenyl]-5-(2-fluorophenyl)sulfonylpyridine
Molecular weight	391.817
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.8
Synonyms	BDBM50205801 (E)-2-(2-chloro-4-fluorostyryl)-5-(2-fluorophenylsulfonyl)pyridine
Inchi Key	AGNKOCOPBGDROC-SOFGYWHQSA-N
Inchi ID	InChI=1S/C19H12ClF2NO2S/c20-17-11-14(21)7-5-13(17)6-8-15-9-10-16(12-23-15)26(24,25)19-4-2-1-3-18(19)22/h1-12H/b8-6+
PubChem CID	44439379
ChEMBL	CHEMBL397112
IUPHAR	N/A
BindingDB	50205801
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5047	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
5046	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
5045	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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