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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-tert-butyl-3-methyl-4-[(4-methylphenyl)sulfonyl]-1H-pyrazol-5-yl thiophene-2-carboxylate
Molecular formula	C20H22N2O4S2
IUPAC name	[2-tert-butyl-5-methyl-4-(4-methylphenyl)sulfonylpyrazol-3-yl] thiophene-2-carboxylate
Molecular weight	418.526
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.4
Synonyms	AC1MMCMW MolPort-003-032-254 CHEMBL1600209 [2-tert-butyl-5-methyl-4-(4-methylphenyl)sulfonylpyrazol-3-yl] thiophene-2-carboxylate MLS000090765 AKOS001197585 SMR000025368 HMS2275I16 MLS001367833 ZINC4118726 MCULE-8597835003 [ Show all ]
Inchi Key	AGRYPPPEOJFIBA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22N2O4S2/c1-13-8-10-15(11-9-13)28(24,25)17-14(2)21-22(20(3,4)5)18(17)26-19(23)16-7-6-12-27-16/h6-12H,1-5H3
PubChem CID	3236657
ChEMBL	CHEMBL1600209
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5159	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
5158	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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