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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000834580
Molecular formula	C25H35N3O4
IUPAC name	(2R,3R,4S)-N-(1H-benzimidazol-2-ylmethyl)-4-cyclohexyl-2-ethoxy-3-(3-hydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxamide
Molecular weight	441.572
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.6
Synonyms	SMR000442127 HMS2198K13 CHEMBL1391645
Inchi Key	AHDYIVBCXUSCMN-MPCDZSKCSA-N
Inchi ID	InChI=1S/C25H35N3O4/c1-2-31-25-18(11-8-14-29)19(17-9-4-3-5-10-17)15-22(32-25)24(30)26-16-23-27-20-12-6-7-13-21(20)28-23/h6-7,12-13,15,17-19,25,29H,2-5,8-11,14,16H2,1H3,(H,26,30)(H,27,28)/t18-,19-,25-/m1/s1
PubChem CID	16197034
ChEMBL	CHEMBL1391645
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5462	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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