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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001028787
Molecular formula	C23H25N5O2S
IUPAC name	2-[3,4-dimethyl-2-(4-methylphenyl)-7-oxopyrazolo[3,4-d]pyridazin-6-yl]-N-(2-thiophen-2-ylethyl)propanamide
Molecular weight	435.546
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.7
Synonyms	CHEMBL1328230 AKOS021938410 SMR000629834 HMS2961I17 2-[3,4-dimethyl-2-(4-methylphenyl)-7-oxo-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl]-N-(2-thien-2-ylethyl)propanamide MolPort-007-767-203 MCULE-5052349710 AKOS001955789 SCHEMBL1494755 [ Show all ]
Inchi Key	AHHKYZOLGMQZAZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25N5O2S/c1-14-7-9-18(10-8-14)27-16(3)20-15(2)25-28(23(30)21(20)26-27)17(4)22(29)24-12-11-19-6-5-13-31-19/h5-10,13,17H,11-12H2,1-4H3,(H,24,29)
PubChem CID	20919877
ChEMBL	CHEMBL1328230
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5552	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463555	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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