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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000673602
Molecular formula	C20H20FN5O4S2
IUPAC name	1-(2-fluorophenyl)-3-(2-hydroxy-1-methyl-5-morpholin-4-ylsulfonylindol-3-yl)iminothiourea
Molecular weight	477.529
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	2.8
Synonyms	1-(2-fluorophenyl)-3-[(Z)-(2-keto-1-methyl-5-morpholinosulfonyl-indolin-3-ylidene)amino]thiourea HMS2699J21 AKOS002107380 MolPort-007-929-441 1-(2-fluorophenyl)-3-[(Z)-(1-methyl-5-morpholin-4-ylsulfonyl-2-oxidanylidene-indol-3-ylidene)amino]thiourea CHEMBL1308615 1-(2-fluorophenyl)-3-[(Z)-[1-methyl-5-(4-morpholinylsulfonyl)-2-oxo-3-indolylidene]amino]thiourea MCULE-8887298835 (3Z)-1-methyl-5-(morpholin-4-ylsulfonyl)-1H-indole-2,3-dione 3-[N-(2-fluorophenyl)thiosemicarbazone] BDBM54336 SMR000314843 1-(2-fluorophenyl)-3-[(Z)-(1-methyl-5-morpholin-4-ylsulfonyl-2-oxoindol-3-ylidene)amino]thiourea cid_16194563 AC1OBCX6 1-(2-fluorophenyl)-3-[(1-methyl-5-morpholin-4-ylsulfonyl-2-oxoindol-3-ylidene)amino]thiourea ZINC100492405 [ Show all ]
Inchi Key	AHYFIPCUISVDBK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20FN5O4S2/c1-25-17-7-6-13(32(28,29)26-8-10-30-11-9-26)12-14(17)18(19(25)27)23-24-20(31)22-16-5-3-2-4-15(16)21/h2-7,12,27H,8-11H2,1H3,(H,22,31)
PubChem CID	4196731
ChEMBL	CHEMBL1308615
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557448	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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