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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1904464
Molecular formula	C24H25ClN4O2S
IUPAC name	4-tert-butyl-N-[[3-[(2-chlorophenyl)methyl]imidazo[4,5-b]pyridin-2-yl]methyl]benzenesulfonamide
Molecular weight	469.0
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.1
Synonyms	HMS1899D05 4-tert-butyl-N-{[3-(2-chlorobenzyl)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}benzenesulfonamide NCGC00134765-01 MCULE-7265581705 AKOS021738571 ZINC8600324 G832-0241 MolPort-010-712-097 [ Show all ]
Inchi Key	AIFPYBQCXIHCTB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25ClN4O2S/c1-24(2,3)18-10-12-19(13-11-18)32(30,31)27-15-22-28-21-9-6-14-26-23(21)29(22)16-17-7-4-5-8-20(17)25/h4-14,27H,15-16H2,1-3H3
PubChem CID	16031205
ChEMBL	CHEMBL1904464
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6166	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463620	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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