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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	L-741604
Molecular formula	C14H17N5
IUPAC name	N,N-dimethyl-2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethanamine
Molecular weight	255.325
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	0.7
Synonyms	L010084 CHEMBL296161 IGNXHSPBUUSUHB-UHFFFAOYSA-N BDBM50060426 N,N-dimethyl-2-[5-(1,2,4-triazol-4-yl)-1H-indol-3-yl]ethylamine D00NLD 154594-22-6 SCHEMBL6943364 Dimethyl-[2-(5-[1,2,4]triazol-4-yl-1H-indol-3-yl)-ethyl]-amine [ Show all ]
Inchi Key	IGNXHSPBUUSUHB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H17N5/c1-18(2)6-5-11-8-15-14-4-3-12(7-13(11)14)19-9-16-17-10-19/h3-4,7-10,15H,5-6H2,1-2H3
PubChem CID	9881526
ChEMBL	CHEMBL296161
IUPHAR	N/A
BindingDB	50060426
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
132701	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
132700	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
132698	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
132703	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
132699	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
132702	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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