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Name | P2Y purinoceptor 14 |
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Species | Homo sapiens (Human) |
Gene | P2RY14 |
Synonym | G-protein coupled receptor 105 GPR105 G protein-coupled receptor 105 P2Y purinoceptor 14 P2Y14 [ Show all ] |
Disease | N/A |
Length | 338 |
Amino acid sequence | MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL |
UniProt | Q15391 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q15391 |
3D structure model | This predicted structure model is from GPCR-EXP Q15391. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4518 |
IUPHAR | 330 |
DrugBank | N/A |
Name | CHEMBL1162557 |
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Molecular formula | C10H19N3O11P2S |
IUPAC name | azane;[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] methyl hydrogen phosphate |
Molecular weight | 451.28 |
Hydrogen bond acceptor | 13 |
Hydrogen bond donor | 6 |
XlogP | None |
Synonyms | N/A |
Inchi Key | DZZPHPIQPUJCSV-BKZSBQMKSA-N |
Inchi ID | InChI=1S/C10H16N2O11P2S.H3N/c1-20-24(16,17)23-25(18,19)21-4-5-7(14)8(15)9(22-5)12-3-2-6(13)11-10(12)26;/h2-3,5,7-9,14-15H,4H2,1H3,(H,16,17)(H,18,19)(H,11,13,26);1H3/t5-,7-,8-,9-;/m1./s1 |
PubChem CID | 44627490 |
ChEMBL | CHEMBL1162557 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
---|---|---|---|
EC50 | 56.0 nM | PMID19902968 | ChEMBL |
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