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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL505727
Molecular formula	C34H32N4O4
IUPAC name	3-[4-[1-(3-ethoxyphenyl)-2-(4-methylphenyl)imidazole-4-carbonyl]piperazin-1-yl]naphthalene-1-carboxylic acid
Molecular weight	560.654
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.2
Synonyms	3-(4-{[1-(3-Ethoxyphenyl)-2-(4-methylphenyl)-1H-imidazol-4-yl]carbonyl}piperazin-1-yl)naphthalene-1-carboxylic acid SCHEMBL502146 BDBM50245180 1-Naphthalenecarboxylic acid,3-[4-[[1-(3-ethoxyphenyl)-2-(4-methylphenyl)-1H-imidazol-4-yl]carbonyl]-1-piperazinyl]- DTXSID6047731 ZINC42834699 3-(4-(1-(3-ethoxyphenyl)-2-p-tolyl-1H-imidazole-4-carbonyl)piperazin-1-yl)-1-naphthoic acid KB-66374 954397-95-6 [ Show all ]
Inchi Key	HMGSYODAZJHCRL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C34H32N4O4/c1-3-42-28-9-6-8-26(20-28)38-22-31(35-32(38)24-13-11-23(2)12-14-24)33(39)37-17-15-36(16-18-37)27-19-25-7-4-5-10-29(25)30(21-27)34(40)41/h4-14,19-22H,3,15-18H2,1-2H3,(H,40,41)
PubChem CID	16755781
ChEMBL	CHEMBL505727
IUPHAR	N/A
BindingDB	50245180
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
118584	Cholecystokinin receptor type A	P32238	CCKAR	Homo sapiens (Human)	428
118585	Cholecystokinin receptor type A	O08786	Cckar	Mus musculus (Mouse)	436
118586	Gastrin/cholecystokinin type B receptor	P32239	CCKBR	Homo sapiens (Human)	447
118587	Gastrin/cholecystokinin type B receptor	P56481	Cckbr	Mus musculus (Mouse)	453

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