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GPCR

NameVasoactive intestinal polypeptide receptor 1
SpeciesRattus norvegicus (Rat)
GeneVipr1
SynonymVIP-R1
VIP-R-1
VIP and PACAP receptor 1
RDC1
PVR2
[ Show all ]
DiseaseN/A for non-human GPCRs
Length459
Amino acid sequenceMRPPSPPHVRWLCVLAGALACALRPAGSQAASPQHECEYLQLIEIQRQQCLEEAQLENETTGCSKMWDNLTCWPTTPRGQAVVLDCPLIFQLFAPIHGYNISRSCTEEGWSQLEPGPYHIACGLNDRASSLDEQQQTKFYNTVKTGYTIGYSLSLASLLVAMAILSLFRKLHCTRNYIHMHLFMSFILRATAVFIKDMALFNSGEIDHCSEASVGCKAAVVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSVFITIWTVVRIYFEDFGCWDTIINSSLWWIIKAPILLSILVNFVLFICIIRILVQKLRPPDIGKNDSSPYSRLAKSTLLLIPLFGIHYVMFAFFPDNFKAQVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWSSKSQHPWGGSNGATCSTQVSMLTRVSPSARRSSSFQAEVSLV
UniProtP30083
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1955712
IUPHAR371
DrugBankN/A

Known ligands

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Total entries: 47
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
106392D structureCHEMBL1956439C18H17ClN2OS344.8573 / 15.1No
207342D structureCHEMBL1956420C21H28O296.4541 / 15.8No
429092D structure61627-58-5C12H14N2OS234.3173 / 13.1Yes
491052D structureCHEMBL1956416C20H25FO300.4172 / 15.6No
554632D structureN-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)cyclopropanecarboxamideC13H14N2OS246.3283 / 13.1Yes
582892D structureCHEMBL1956434C19H20N2OS324.4423 / 14.9Yes
705752D structureCHEMBL1956429C14H18N2OS262.3713 / 13.9Yes
753952D structureCHEMBL1956413C21H28OS328.5142 / 16.0No
796532D structureCHEMBL1956431C14H16N2OS260.3553 / 13.6Yes
930172D structureCHEMBL1956444C19H18N2OS322.4263 / 14.6Yes
946302D structureCHEMBL1956419C22H31NO325.4962 / 15.6No
1047002D structureCHEMBL1956257C21H25F3O350.4254 / 16.3No
1051682D structureCHEMBL1956422C21H28O296.4541 / 15.8No
1071052D structureCHEMBL1956443C20H20N2OS336.4533 / 14.9Yes
1096892D structureBAS 01506027C16H20N2OS288.4093 / 14.7Yes
1120992D structureCHEMBL1956442C19H17N3OS335.4253 / 24.4Yes
1147002D structureCHEMBL1956412C21H28O2312.4532 / 15.4No
1499312D structureCHEMBL1956433C18H18N2OS310.4153 / 14.5Yes
1536952D structureCHEMBL1956436C19H20N2OS324.4423 / 14.9Yes
5541462D structureSecrepanC130H219N43O423056.4448 / 52-13.4No
1740852D structureCHEMBL1956259C26H30O358.5251 / 17.1No
2010502D structureCHEMBL1956417C26H30O358.5251 / 17.1No
2102252D structureCHEMBL1956437C19H20N2O2S340.4414 / 14.5Yes
2201662D structureCHEMBL1956425C24H28O332.4871 / 16.7No
2434682D structure23903-48-2C16H14N2OS282.3613 / 14.3Yes
2497632D structureCHEMBL1956415C21H28O2312.4532 / 15.4No
2585682D structureCHEMBL1956432C15H18N2OS274.3823 / 14.2Yes
2633342D structureN-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)acetamideC11H12N2OS220.293 / 12.6Yes
2654292D structureCHEMBL1956421C20H25ClO316.8691 / 16.1No
2730962D structureCHEMBL1956438C19H20N2O2S340.4414 / 14.5Yes
2786572D structureCHEMBL1956445C17H16N2O2S312.3874 / 14.3Yes
3001132D structureCHEMBL1956256C21H28O296.4541 / 15.8No
5547952D structurepituitary adenylate cyclase activating polypeptide-27C142H224N40O39S3147.6647 / 48-10.3No
3099832D structureCHEMBL1956423C26H30O358.5251 / 17.1No
3117942D structureCHEMBL1956441C19H18N2O2S338.4254 / 14.3Yes
3140722D structureCHEMBL1956414C21H28O2312.4532 / 15.4No
5548692D structureHeloderminC176H285N47O493843.555 / 53-9.7No
3446782D structureCHEMBL1956424C24H28O332.4871 / 16.7No
3504152D structureCHEMBL1956440C19H16N2OS2352.474 / 15.3No
5550382D structureBDBM81828C147H237N43O43S3326.8351 / 49-16.6No
3643302D structureCHEMBL1956435C19H20N2OS324.4423 / 14.9Yes
3715012D structureCHEMBL1632048C13H16N2OS248.3443 / 13.7Yes
3868362D structureCHEMBL397167C17H16N2OS296.3883 / 14.2Yes
3889792D structureCHEMBL1956258C21H25NO307.4372 / 15.2No
3912182D structureCHEMBL1956427C22H30O310.4811 / 16.2No
4325452D structureCHEMBL1956418C20H26O282.4271 / 15.5No
4401302D structureCHEMBL1956426C20H25ClO316.8691 / 16.1No

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