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Name | Vasoactive intestinal polypeptide receptor 1 |
---|---|
Species | Rattus norvegicus (Rat) |
Gene | Vipr1 |
Synonym | VIP-R1 VIP-R-1 VIP and PACAP receptor 1 RDC1 PVR2 [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 459 |
Amino acid sequence | MRPPSPPHVRWLCVLAGALACALRPAGSQAASPQHECEYLQLIEIQRQQCLEEAQLENETTGCSKMWDNLTCWPTTPRGQAVVLDCPLIFQLFAPIHGYNISRSCTEEGWSQLEPGPYHIACGLNDRASSLDEQQQTKFYNTVKTGYTIGYSLSLASLLVAMAILSLFRKLHCTRNYIHMHLFMSFILRATAVFIKDMALFNSGEIDHCSEASVGCKAAVVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSVFITIWTVVRIYFEDFGCWDTIINSSLWWIIKAPILLSILVNFVLFICIIRILVQKLRPPDIGKNDSSPYSRLAKSTLLLIPLFGIHYVMFAFFPDNFKAQVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWSSKSQHPWGGSNGATCSTQVSMLTRVSPSARRSSSFQAEVSLV |
UniProt | P30083 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL1955712 |
IUPHAR | 371 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
10639 | CHEMBL1956439 | C18H17ClN2OS | 344.857 | 3 / 1 | 5.1 | No |
20734 | CHEMBL1956420 | C21H28O | 296.454 | 1 / 1 | 5.8 | No |
42909 | 61627-58-5 | C12H14N2OS | 234.317 | 3 / 1 | 3.1 | Yes |
49105 | CHEMBL1956416 | C20H25FO | 300.417 | 2 / 1 | 5.6 | No |
55463 | N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)cyclopropanecarboxamide | C13H14N2OS | 246.328 | 3 / 1 | 3.1 | Yes |
58289 | CHEMBL1956434 | C19H20N2OS | 324.442 | 3 / 1 | 4.9 | Yes |
70575 | CHEMBL1956429 | C14H18N2OS | 262.371 | 3 / 1 | 3.9 | Yes |
75395 | CHEMBL1956413 | C21H28OS | 328.514 | 2 / 1 | 6.0 | No |
79653 | CHEMBL1956431 | C14H16N2OS | 260.355 | 3 / 1 | 3.6 | Yes |
93017 | CHEMBL1956444 | C19H18N2OS | 322.426 | 3 / 1 | 4.6 | Yes |
94630 | CHEMBL1956419 | C22H31NO | 325.496 | 2 / 1 | 5.6 | No |
104700 | CHEMBL1956257 | C21H25F3O | 350.425 | 4 / 1 | 6.3 | No |
105168 | CHEMBL1956422 | C21H28O | 296.454 | 1 / 1 | 5.8 | No |
107105 | CHEMBL1956443 | C20H20N2OS | 336.453 | 3 / 1 | 4.9 | Yes |
109689 | BAS 01506027 | C16H20N2OS | 288.409 | 3 / 1 | 4.7 | Yes |
112099 | CHEMBL1956442 | C19H17N3OS | 335.425 | 3 / 2 | 4.4 | Yes |
114700 | CHEMBL1956412 | C21H28O2 | 312.453 | 2 / 1 | 5.4 | No |
149931 | CHEMBL1956433 | C18H18N2OS | 310.415 | 3 / 1 | 4.5 | Yes |
153695 | CHEMBL1956436 | C19H20N2OS | 324.442 | 3 / 1 | 4.9 | Yes |
554146 | Secrepan | C130H219N43O42 | 3056.44 | 48 / 52 | -13.4 | No |
174085 | CHEMBL1956259 | C26H30O | 358.525 | 1 / 1 | 7.1 | No |
201050 | CHEMBL1956417 | C26H30O | 358.525 | 1 / 1 | 7.1 | No |
210225 | CHEMBL1956437 | C19H20N2O2S | 340.441 | 4 / 1 | 4.5 | Yes |
220166 | CHEMBL1956425 | C24H28O | 332.487 | 1 / 1 | 6.7 | No |
243468 | 23903-48-2 | C16H14N2OS | 282.361 | 3 / 1 | 4.3 | Yes |
249763 | CHEMBL1956415 | C21H28O2 | 312.453 | 2 / 1 | 5.4 | No |
258568 | CHEMBL1956432 | C15H18N2OS | 274.382 | 3 / 1 | 4.2 | Yes |
263334 | N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)acetamide | C11H12N2OS | 220.29 | 3 / 1 | 2.6 | Yes |
265429 | CHEMBL1956421 | C20H25ClO | 316.869 | 1 / 1 | 6.1 | No |
273096 | CHEMBL1956438 | C19H20N2O2S | 340.441 | 4 / 1 | 4.5 | Yes |
278657 | CHEMBL1956445 | C17H16N2O2S | 312.387 | 4 / 1 | 4.3 | Yes |
300113 | CHEMBL1956256 | C21H28O | 296.454 | 1 / 1 | 5.8 | No |
554795 | pituitary adenylate cyclase activating polypeptide-27 | C142H224N40O39S | 3147.66 | 47 / 48 | -10.3 | No |
309983 | CHEMBL1956423 | C26H30O | 358.525 | 1 / 1 | 7.1 | No |
311794 | CHEMBL1956441 | C19H18N2O2S | 338.425 | 4 / 1 | 4.3 | Yes |
314072 | CHEMBL1956414 | C21H28O2 | 312.453 | 2 / 1 | 5.4 | No |
554869 | Helodermin | C176H285N47O49 | 3843.5 | 55 / 53 | -9.7 | No |
344678 | CHEMBL1956424 | C24H28O | 332.487 | 1 / 1 | 6.7 | No |
350415 | CHEMBL1956440 | C19H16N2OS2 | 352.47 | 4 / 1 | 5.3 | No |
555038 | BDBM81828 | C147H237N43O43S | 3326.83 | 51 / 49 | -16.6 | No |
364330 | CHEMBL1956435 | C19H20N2OS | 324.442 | 3 / 1 | 4.9 | Yes |
371501 | CHEMBL1632048 | C13H16N2OS | 248.344 | 3 / 1 | 3.7 | Yes |
386836 | CHEMBL397167 | C17H16N2OS | 296.388 | 3 / 1 | 4.2 | Yes |
388979 | CHEMBL1956258 | C21H25NO | 307.437 | 2 / 1 | 5.2 | No |
391218 | CHEMBL1956427 | C22H30O | 310.481 | 1 / 1 | 6.2 | No |
432545 | CHEMBL1956418 | C20H26O | 282.427 | 1 / 1 | 5.5 | No |
440130 | CHEMBL1956426 | C20H25ClO | 316.869 | 1 / 1 | 6.1 | No |
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