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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL225124
Molecular formula	C17H13FN4OS
IUPAC name	13-(dimethylamino)-5-(4-fluorophenyl)-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one
Molecular weight	340.376
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	3.3
Synonyms	9-dimethylamino-3-(p-fluorophenyl)-3H-5-thia-1,3,6-triazafluoren-4-one BDBM50177078 SCHEMBL8235293 9-Dimethylamino-3-(4-fluoro-phenyl)-3H-pyrido[3'',2'':4,5]thieno[3,2-d]pyrimidin-4-one
Inchi Key	BHOLPZFHFOLKCI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H13FN4OS/c1-21(2)12-7-8-19-16-13(12)14-15(24-16)17(23)22(9-20-14)11-5-3-10(18)4-6-11/h3-9H,1-2H3
PubChem CID	11667270
ChEMBL	CHEMBL225124
IUPHAR	N/A
BindingDB	50177078
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23923	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
23925	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
23922	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
23924	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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