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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL346633
Molecular formula	C28H32N2
IUPAC name	(2R,3R)-2-benzhydryl-N-[(2-methylphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine
Molecular weight	396.578
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	5.8
Synonyms	BDBM50280469 [(2R,3R)-2-(2,2-Diphenyl-ethyl)-1-aza-bicyclo[2.2.2]oct-3-yl]-(2-methyl-benzyl)-amine
Inchi Key	KHWRHXNNDGPGGG-VSGBNLITSA-N
Inchi ID	InChI=1S/C28H32N2/c1-21-10-8-9-15-25(21)20-29-27-24-16-18-30(19-17-24)28(27)26(22-11-4-2-5-12-22)23-13-6-3-7-14-23/h2-15,24,26-29H,16-20H2,1H3/t27-,28-/m1/s1
PubChem CID	15037919
ChEMBL	CHEMBL346633
IUPHAR	N/A
BindingDB	50280469
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
169541	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
169540	Substance-K receptor	P51144	TACR2	Mesocricetus auratus (Golden hamster)	384
169539	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407
169542	Substance-P receptor	P14600	Tacr1	Rattus norvegicus (Rat)	407

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